Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ‐Fluoro Enals - Archive ouverte HAL
Article Dans Une Revue Chemistry - A European Journal Année : 2024

Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ‐Fluoro Enals

Résumé

We describe the direct synthesis of γ‐fluoro enals from the corresponding silyl dienol ethers. This simple process operates under mild conditions and is compatible with a wide range of functionalities. The high γ regioselectivity of this protocol was rationalized by means of theoretical calculations.

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Chimie
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Dates et versions

hal-04404468 , version 1 (11-03-2024)

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Yang Li, Marina Briand, Karinne Miqueu, Elsa Anselmi, Emmanuel Magnier, et al.. Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ‐Fluoro Enals. Chemistry - A European Journal, 2024, 30 (10), pp.e202303545. ⟨10.1002/chem.202303545⟩. ⟨hal-04404468⟩
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