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Article Dans Une Revue Nucleic Acids Research Année : 2024

HumanLectome, an update of UniLectin for the annotation and prediction of human lectins

Résumé

T he UniL ectin portal (ht tps://unilectin.unige.c h/) was designed in 2019 with the goal of centralising curated and predicted data on carboh y dratebinding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (ht tps://unilectin.unige.c h/humanL ectome/), co v ering our knowledge of the human lectome and comprising 215 une v enly characterised lectins, particularly in terms of str uct ural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-str uct ure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined.

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Chimie
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Dates et versions

hal-04376368 , version 1 (06-01-2024)

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Boris Schnider, Yacine M’rad, Jalaa El Ahmadie, Alexandre G de Brevern, Anne Imberty, et al.. HumanLectome, an update of UniLectin for the annotation and prediction of human lectins. Nucleic Acids Research, 2024, 52 (D1), pp.D1683 - D1693. ⟨10.1093/nar/gkad905⟩. ⟨hal-04376368⟩
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