Numerical solutions of a 2D fluid problem coupled to a nonlinear non-local reaction-advection-diffusion problem for cell crawling migration in a discoidal domain - Archive ouverte HAL
Article Dans Une Revue International Journal of Mathematical Models and Methods in Applied Sciences Année : 2018

Numerical solutions of a 2D fluid problem coupled to a nonlinear non-local reaction-advection-diffusion problem for cell crawling migration in a discoidal domain

Résumé

In this work, we present a numerical scheme for the approximate solutions of a 2D crawling cell migration problem. The model, defined on a non-deformable discoidal domain, consists in a Darcy fluid problem coupled with a Poisson problem and a reaction-advection-diffusion problem. Moreover, the advection velocity depends on boundary values, making the problem nonlinear and non local. \parFor a discoidal domain, numerical solutions can be obtained using the finite volume method on the polar formulation of the model. Simulations show that different migration behaviours can be captured.

Dates et versions

hal-04360681 , version 1 (21-12-2023)

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Christèle Etchegaray, Nicolas Meunier. Numerical solutions of a 2D fluid problem coupled to a nonlinear non-local reaction-advection-diffusion problem for cell crawling migration in a discoidal domain. International Journal of Mathematical Models and Methods in Applied Sciences, 2018. ⟨hal-04360681⟩
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