Prevalence, Characteristics and Preoperative Predictors of Chronic Pain After Double-Lung Transplantation: A Prospective Cohort Study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Cardiothoracic and Vascular Anesthesia Année : 2022

Prevalence, Characteristics and Preoperative Predictors of Chronic Pain After Double-Lung Transplantation: A Prospective Cohort Study

Résumé

Abstract Objective: Data on chronic pain after lung transplantation are heterogeneous. This study prospectively explored the prevalence, characteristics, consequences, and preoperative predictors of pain in lung transplant recipients. Design: A prospective cohort study. Setting: The Foch University Hospital, Suresnes, France. Participants: Patients registered on the waiting list for double-lung transplantation in the authors' institution from August 2008 to October 2013 and transplanted. Interventions: Database prospectively completed in real time during consultations with a pain-certified anesthesiologist before lung transplantation and six months after surgery. Measurements and main results: The assessments explored pain in three components: physical (intensity, location, neuropathic and sensory qualifications, treatments), mental (anxiety and depression), and quality of life. Seventy-two patients underwent all assessments. The prevalence of six-month postoperative pain was 68.0%. Among patients with pain, 83.3% reported mild average pain and 26.5% had neuropathic pain. All patients who responded to the questionnaire took analgesics frequently, but only 9.1% took opioids. Patients with pain reported higher levels of anxiety (p = 0.02) and depression (p = 0.01). Additionally, they presented with increased difficulty in ambulation (p = 0.03), work (p = 0.02), and sleep (p = 0.02). The maximum level of preoperative pain was an independent risk factor of six-month postoperative pain (p = 0.03). Conclusions: The authors report a high prevalence of chronic pain with concomitant psychosocial repercussions despite a reported mild intensity. Perioperative measures, such as personalized and detailed management plans, could improve patient satisfaction. Keywords: cystic fibrosis; lung transplantation; pain; quality of life.

Dates et versions

hal-04360594 , version 1 (21-12-2023)

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Quentin Laurent, Mireille Michel-Cherqui, Barbara Szekely, Matthieu Glorion, Édouard Sage, et al.. Prevalence, Characteristics and Preoperative Predictors of Chronic Pain After Double-Lung Transplantation: A Prospective Cohort Study. Journal of Cardiothoracic and Vascular Anesthesia, 2022, 36 (2), pp.500-509. ⟨10.1053/j.jvca.2021.07.041⟩. ⟨hal-04360594⟩
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