Poster De Conférence Année : 2023

Role of biotransformation in the mutagenicity of Versicolorin A, a precursor of Aflatoxin B1

Résumé

Aflatoxin B1 (AFB1) exhibits the most severe toxicological effects of all known mycotoxins. Versicolorin A (VerA) is a precursor in the biosynthesis of AFB1. Both toxins are produced by the same aflatoxigenic species and can therefore co-contaminate food commodities. It is well established that the in vivo bioactivation of AFB1 into a highly reactive molecule is the key step in the mutagenic process. In contrast, much less is known about the toxicity of VerA and no information is available on its metabolization.

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hal-04357518 , version 1 (21-12-2023)

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  • HAL Id : hal-04357518 , version 1

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Carine Al-Ayoubi, Justin Oules, Elodie Person, Sandrine S. Bruel, Alyssa Bouville, et al.. Role of biotransformation in the mutagenicity of Versicolorin A, a precursor of Aflatoxin B1. Mycotoxins and Phycotoxins Gordon Research Conference, Jun 2023, Boston, United States. ⟨hal-04357518⟩
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