Decolonial and South epistemologies criticize the inequality and coloniality of knowledge production throughout the world. From this perspective, this contribution focuses on the Horizon 2020 fundings: studying the researched spaces and how the fundings and the projects work highlights the tension between the universality principle of science and the eurocentrism of European research. This presentation relies on research on the over-researching of spaces (Aiken 2022), the spaces representations (Didelon-Loiseau 2022), and scientometrics (Castro Torres et Alburez-Gutierrez 2022). As the rest of the world is mostly excluded from the coordination of research projects funded by the EU, I aim to question the consequences of these inequalities concerning coordination and collaboration on scientific production.