This article is a first attempt towards building an integrative analytical framework to study goalorientated transformative change (GOTC) processes, defined as system-transforming processes that are guided by the ambition to resolve current or expected future societal challenges. GOTC can only start once a broad range of possible goals are considered by key stakeholders and major relevant actors are committed to act. Hence, there is a need for widening the scope of the current, partial conceptual models to consider the co-evolutionary interactions between technology, economy, and society to better understand and effectively guide and/or assess GOTC. This claim is based on our focussed review of Innovation Studies, Social Innovation, and Sustainability Transitions research. We offer four building blocks for a new, integrative framework to analyse GOTC: its overarching goal; objects, types, and levels of change; mechanisms of change; and a set of criteria to assess change.