Multiphase flows in complex porous networks occur in many natural processes and engineering applications. We present an analytical, experimental and numerical investigation of slow drainage in porous media that exhibit a gradient in grain size. We show that the effect of such structural gradient is similar to that of an external force field on the obtained drainage patterns, when it either stabilises or destabilises the invasion front. For instance, gravity can enhance or reverse the drainage pattern in graded porous media. In particular, we show that the width of stable drainage fronts scales both with the spatial gradient of the necessary pressure for pore invasion and with the local distribution of this (disordered) threshold. The scaling exponent results from percolation theory and is − 0.57 for 2D systems. Overall, introducing a dimensionless Fluctuation number, we propose a unifying theory for the up-scaling of dual immiscible fluid flows covering most classical scenarii.