On 2 December 2020 10:54 UTC a shallow earthquake of M W (NOA) = 4.6 occurred near the village of Kallithea (to the east of Thiva), central Greece, which, despite its modest size, was locally damaging. Using InSAR and GNSS data, we mapped a permanent change on the ground surface, i.e., a subsidence of 7 cm. Our geodetic inversion modelling indicates that the rupture occurred on a WNW–ESE striking, SSW-dipping normal fault, with a dip-angle of ~ 54°. The maximum slip value was 0.35 m, which was reached at a depth of about 1100 m. The analysis of broadband seismological data also provided kinematic source parameters such as moment magnitude M W = 4.6 (± 0.1), rupture area 6.3 km 2 and mean slip 0.16 m, which agree with the values obtained from the geodetic model. The effects of the earthquake were disproportionate to its moderate magnitude, probably due to its unusually shallow depth (slip centroid at 1.1 km) and the high efficiency of the earthquake (radiation efficiency $$\eta$$ η = 0.62). The geodetic data inversion also indicates that within the uncertainty limits of the technique, three scenarios are possible (a) the earthquake responsible for the mapped surface deformation may have occurred on a ~ 2-km long, blind normal fault different from the well-known active Kallithea normal fault or (b) could have occurred along a secondary fault that branches off the Kallithea fault or (c) it may have occurred along the Kallithea fault itself, but with its geometrical configuration could not be modelled with available data. We have also concluded that with a high dip-angle Kallithea Fault forward model it is not possible to fit the geodetic data. The rupture initiated at a very shallow depth (1.1 km) and it could not propagate deeper possibly because of a structural barrier down-dip. The 2020 event near Kallithea highlighted the structural complexity in this region of the Asopos Rift valley as the reactivation of the WNW–ESE structures indicates their significant role in strain accommodation and that they still represent a seismic hazard for this region.