The Silene latifolia genome and its giant Y chromosome - Archive ouverte HAL Access content directly
Preprints, Working Papers, ... Year : 2023

The Silene latifolia genome and its giant Y chromosome

1 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558
2 ICIn - UOH - Instituto de Ciencias de la Ingenieria
3 iBio - Instituto Milenio de Biología Integrativa = Millennium Institute for Integrative Biology
4 CIBIO - Centro de Investigação em Biodiversidade e Recursos Genéticos [Vairao]
5 FCUP - Faculdade de Ciências da Universidade do Porto
6 ESE - Ecologie Systématique et Evolution
7 VUB - Vrije Universiteit Brussel [Bruxelles]
8 IBP / CAS - Institute of Biophysics of the Czech Academy of Sciences
9 CEFE - Centre d’Ecologie Fonctionnelle et Evolutive
10 IPS2 (UMR_9213 / UMR_1403) - Institut des Sciences des Plantes de Paris-Saclay
11 UCPH - University of Copenhagen = Københavns Universitet
12 GenScale - Scalable, Optimized and Parallel Algorithms for Genomics
13 CSU - Colorado State University [Fort Collins]
14 GENOSCOPE - Genoscope - Centre national de séquençage [Evry]
15 LBGB - Laboratoire de Bioinformatique pour la Génomique et la Biodiversité
16 DTAMB - Développement de Techniques et Analyse Moléculaire de la Biodiversité [Lyon]
17 UMR AGAP - Amélioration génétique et adaptation des plantes méditerranéennes et tropicales
18 Département écologie évolutive [LBBE]
19 EBC - Department of Ecology and Genetics [Uppsala]
20 EFOR Group
21 EGCE - Evolution, génomes, comportement et écologie
22 Columbia University [New York]
23 SVQV - Santé de la vigne et qualité du vin
24 University of Louisville School of Medicine [Louisville]
25 IEB / CAS - Institute of Experimental Botany of the Czech Academy of Sciences
26 University of Virginia
27 TTU - Texas Tech University [Lubbock]
28 Uppsala Universitet [Uppsala]
29 JACOB - Institut de Biologie François JACOB
30 CEA - Commissariat à l'énergie atomique et aux énergies alternatives
31 Universidade do Porto = University of Porto
Paris Veltsos
Peter Fields
Radim Cegan
Ricardo de la Vega
Amine Chebbi
  • Function : Author
Djivan Prentout
Matthew Olson
Daniel Sloan
Sophie Karrenberg
Lynda Delph
Tatiana Giraud
Alex Di Genova

Abstract

Abstract In some species, the Y is a tiny chromosome but the dioecious plant Silene latifolia has a giant ∼550 Mb Y chromosome, which has remained unsequenced so far. Here we used a hybrid approach to obtain a high-quality male S. latifolia genome. Using mutants for sexual phenotype, we identified candidate sex-determining genes on the Y. Comparative analysis of the sex chromosomes with outgroups showed the Y is surprisingly rearranged and degenerated for a ∼11 MY-old system. Recombination suppression between X and Y extended in a stepwise process, and triggered a massive accumulation of repeats on the Y, as well as in the non-recombining pericentromeric region of the X, leading to giant sex chromosomes. One-Sentence Summary This work uncovers the structure, function, and evolution of one of the largest giant Y chromosomes, that of the model plant Silene latifolia , which is almost 10 times larger than the human Y, despite similar genome sizes.

Dates and versions

hal-04293712 , version 1 (19-11-2023)

Licence

Identifiers

Cite

Carol Moraga, Catarina Branco, Quentin Rougemont, Paris Veltsos, Pavel Jedlička, et al.. The Silene latifolia genome and its giant Y chromosome. 2023. ⟨hal-04293712⟩
94 View
0 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More