Current issues related to motor sequence learning in humans
Résumé
The learning of sequential motor behaviors involves the
integration of separate movements into a unified and
coordinated sequence of actions through practice.
Neuroimaging studies in humans strongly suggest that this
form of procedural memory relies on the progressive
reorganization of motor-related neural networks over the
course of learning. This experience-driven reorganization of
internal task representations is also subserved by consolidation
processes that require time, and sometimes sleep, to become
effective, hence constituting the mechanism by which long-
term memory of the skill is achieved. In this review, we present
the current understanding of the behavioral determinants, brain
functional plasticity and neurophysiological processes related
to the formation and long-term retention of motor sequence
knowledge. Insights from clinical research and their
practical implications, with the development of non-invasive
and patient-oriented interventions, are also discussed.