The paper gives an overview of 3D GPR experiment to survey debonding areas within pavement structure during accelerated pavement testing on the IFSTTAR’s fatigue carrousel. Several artificial defects (tack-free, geotextile and sand-based) have been embedded during the construction phase between the top and the base layers. The data collection was organized in a two-stage experiments and covers the full life-cycle of the pavement structure. During the first stage that took place in 2012-13 leading to 300 kloading cycles, the structure revealed no clear degradation. Then, the second measurement campaign was performed in 2019 and lasted up to 720k loadings, until revealing a strongly degraded pavement surface. 3D GPR data were collected at 396, 500, 600 and 720 kloading cycles. They were completed by conventional 2D ground-coupled 1.5 and 2.6 GHz measurements in transverse and longitudinal directions. Radar data at 1.5 GHz are processed and compared on the three major defects.