Phytoprostanes and phytofurans: Bioactive compounds in aerial parts of Acacia cyanophylla Lindl
Résumé
The relevance of oxylipins as biomarkers of oxidative stress has been established in recent years. Phytoprostanes and phytofurans are plant metabolites derived from peroxidation of α-linolenic acid (ALA) induced by ROS. Previous findings have suggested new valuable biological properties for these new active compounds in the frame of diverse pathophysiological situations and health constraints. Lipidomic profiling of different aerial parts of the same Acacia cyanophylla Lindl. specimen, was evaluated for the first time here, using LC-MS/MS technology. Analysis revealed the existence of six PhytoPs and three PhytoFs. Stems have the highest amount of these metabolites with 179.35 ng/g and 320.79 ng/g respectively. This first complete profile paves the way to explore Acacia cyanophylla Lindl. as a source of plant oxylipins for therapeutic or pharmaceutical uses.
Domaines
Chimie thérapeutique
Fichier principal
Fitoterapia_mersni_HAL_2023.pdf (896.71 Ko)
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SUPPLEMENTARY DATA.pdf (761.58 Ko)
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