SCCS OPINION on Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165) (CAS/EC No. 73793-79-0/827-723-1 and 1928659-47-5/-) - SCCS/1659/23 - Preliminary Opinion
Abstract
SCCS OPINION on Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165) (CAS/EC No. 73793-79-0/827-723-1 and 1928659-47-5/-) - SCCS/1659/23 - Preliminary Opinion
U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, M. Dusinska, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von Goetz
The SCCS adopted this document during its plenary meeting on 26 October 2023 (46 pages)
Mise en ligne : 6th November 2023
https://health.ec.europa.eu/publications/hydroxypropyl-p-phenylenediamine-and-its-dihydrochloride-salt-a165-casec-no-73793-79-0827-723-1-and_en
https://health.ec.europa.eu/system/files/2023-11/sccs_o_280.pdf
Details
Publication date : 6th November 2023
Author : Scientific Committee on Consumer Safety (SCCS)
Description
SCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), M. Dusinska (Rapporteur), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven
SCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von Goetz
Contact: SANTE-SCCS@ec.europa.eu
On request from: European Commission
SCCS Number: SCCS/1659/23
Adopted on: 26 October 2023
Conclusion of the opinion:
(1) In light of the data provided, does the SCCS consider Hydroxypropyl p-phenylenediamine and its dihydrochloride salt safe when used in oxidative hair colouring products up to a maximum on-head concentration of 2 %?
In light of the data provided, the SCCS considers that hydroxypropyl p-phenylenediamine and its dihydrochloride salt are safe when used in oxidative hair colouring products up to a maximum on-head concentration of 2%
(2) Does the SCCS have any further scientific concerns with regard to the use of Hydroxypropyl p-phenylenediamine and its dihydrochloride salt in cosmetic products?
A mild to moderate eye irritation potential of the test item cannot be excluded. Hydroxypropyl p-phenylenediamine and its dihydrochloride salt is a moderate skin sensitiser based on animal data.
Keywords:
SCCS, scientific opinion, Hydroxypropyl p-phenylenediamine and its dihydrochloride salt, A165, CAS/EC No. 73793-79-0/827-723-1 and 1928659-47-5/-, Regulation 1223/2009
Opinion to be cited as:
SCCS (Scientific Committee on Consumer Safety), Opinion on Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165) (CAS/EC No. 73793-79-0/827-723-1 and 1928659-47-5/-), preliminary version of 26 October 2023, SCCS/1659/23
Origin : Publisher files allowed on an open archive
Licence : CC BY NC SA - Attribution - NonCommercial - ShareAlike
Licence : CC BY NC SA - Attribution - NonCommercial - ShareAlike