Synthesis of 4-Phosphonylpyrrolidin-3-ones via [3+2] Cycloaddition of Nitrones with Phosphinylallenes - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Advanced Synthesis and Catalysis Année : 2023

Synthesis of 4-Phosphonylpyrrolidin-3-ones via [3+2] Cycloaddition of Nitrones with Phosphinylallenes

Résumé

A variety of 4-phosphinylpyrrolidin-3-ones was prepared in good yields and excellent diastereoselectivity via a [3+2] cycloaddition between aryl aldonitrones and phosphinylallenes. Under the reaction conditions, the cycloadducts directly undergo a rearrangement to afford selectively the corresponding pyrrolidin-3-ones. DFT calculations provide some insights into the mechanism.
Fichier principal
Vignette du fichier
Rayhane.pdf (1.2 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04251090 , version 1 (20-10-2023)

Identifiants

Citer

Rayhane Hammami, Pascale Maldivi, Christian Philouze, Sébastien Carret, Benjamin Darses, et al.. Synthesis of 4-Phosphonylpyrrolidin-3-ones via [3+2] Cycloaddition of Nitrones with Phosphinylallenes. Advanced Synthesis and Catalysis, 2023, 365 (9), pp.1385-1390. ⟨10.1002/adsc.202⟩. ⟨hal-04251090⟩
38 Consultations
26 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More