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Article Dans Une Revue Antimicrobial Agents and Chemotherapy Année : 2019

Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations

Résumé

Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients. Recently, several clinical trials of “universal” drug regimens, aiming to treat drug-susceptible and drug-resistant TB, have included a fluoroquinolone.

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Pharmacologie

Dates et versions

hal-04248658 , version 1 (18-10-2023)

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Citer

Jansy Sarathy, Landry Blanc, Nadine Alvarez-Cabrera, Paul O’brien, Isabela Dias-Freedman, et al.. Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations. Antimicrobial Agents and Chemotherapy, 2019, 63 (5), ⟨10.1128/AAC.02516-18⟩. ⟨hal-04248658⟩

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