Mechanisms of eukaryotic transcription termination at a glance - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Cell Science Année : 2023

Mechanisms of eukaryotic transcription termination at a glance

Résumé

Transcription termination is the final step of a transcription cycle, which induces the release of the transcript at the termination site and allows the recycling of the polymerase for the next round of transcription. Timely transcription termination is critical for avoiding interferences between neighbouring transcription units as well as conflicts between transcribing RNA polymerases (RNAPs) and other DNA-associated processes, such as replication or DNA repair. Understanding the mechanisms by which the very stable transcription elongation complex is dismantled is essential for appreciating how physiological gene expression is maintained and also how concurrent processes that occur synchronously on the DNA are coordinated. Although the strategies employed by the different classes of eukaryotic RNAPs are traditionally considered to be different, novel findings point to interesting commonalities. In this Cell Science at a Glance and the accompanying poster, we review the current understanding about the mechanisms of transcription termination by the three eukaryotic RNAPs.
Fichier sous embargo
Fichier sous embargo
0 4 18
Année Mois Jours
Avant la publication
dimanche 3 novembre 2024
Fichier sous embargo
dimanche 3 novembre 2024
Connectez-vous pour demander l'accès au fichier

Dates et versions

hal-04247855 , version 1 (30-10-2023)

Identifiants

Citer

Juanjuan Xie, Domenico Libri, Odil Porrua. Mechanisms of eukaryotic transcription termination at a glance. Journal of Cell Science, 2023, 136 (1), ⟨10.1242/jcs.259873⟩. ⟨hal-04247855⟩
24 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More