Synthesis, Characterisation, and in vitro Cytotoxic Activity of Dithiocarbamato Glycoconjugate Half‐Sandwich Ruthenium and Osmium Complexes
Résumé
The synthesis by transmetallation and in‐depth characterisation by IR spectroscopy of five half‐sandwich ruthenium and osmium dithiocarbamato isonipecotamide glycoconjugate complexes are presented herein. The evaluation of their in vitro cytotoxicity and of the zinc precursors’ in vitro cytotoxicity towards ovarian cancer (A2780 and A2780cisR) and normal prostate (PNT2) cells is reported. While the cytotoxicity of the compounds is rather limited, some selectivity is observed.
Domaines
Chimie
Fichier principal
Helvetica Chimica Acta - 2023 - Soldevila‐Barreda - Synthesis Characterisation and in vitro Cytotoxic Activity of.pdf (8.32 Mo)
Télécharger le fichier
Origine | Publication financée par une institution |
---|