A branching model for intergenerational telomere length dynamics

We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean telomere length and its age. We study its Malthusian's behaviour and provide numerical simulations to understand the influence of biologically relevant parameters.

Mots clés

Telomer Branching process age-dependence Individual based model IBM

Domaines

Probabilités [math.PR] Sciences du Vivant [q-bio]

Fichier principal

2023_10_15_Intergen_telo_dyn.pdf (621.56 Ko)

Origine	Fichiers produits par l'(les) auteur(s)

Denis Villemonais : Connectez-vous pour contacter le contributeur

https://hal.science/hal-04242595

Soumis le : mardi 14 novembre 2023-16:14:09

Dernière modification le : jeudi 14 novembre 2024-15:54:02

Dates et versions

hal-04242595 , version 1 (15-10-2023)

hal-04242595 , version 2 (14-11-2023)

Identifiants

HAL Id : hal-04242595 , version 2
ARXIV : 2311.09678
DOI : 10.48550/arXiv.2311.09678

Citer

Athanasios Benetos, Olivier Coudray, Anne Gégout-Petit, Lionel Lenôtre, Simon Toupance, et al.. A branching model for intergenerational telomere length dynamics. 2023. ⟨hal-04242595v2⟩

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