The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?
Résumé
Meiotic crossovers, which are exchanges of genetic material between homologous chromosomes, are more evenly and distantly spaced along chromosomes than expected by chance. This is because the occurrence of one crossover reduces the likelihood of nearby crossover events-a conserved and intriguing phenomenon called crossover interference. Although crossover interference was first described over a century ago, the mechanism allowing coordination of the fate of potential crossover
Domaines
Reproduction sexuée
Fichier principal
The mechanisms regulating meiotic crossovers_HAL.pdf (4.09 Mo)
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