A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis - Archive ouverte HAL
Article Dans Une Revue Cell Reports Année : 2023

A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis

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Highlights d Copper transporter CTR1 is the sole receptor for the endogenous retroviral Env Refrex1 d Refrex1 controls CTR1-dependent copper accumulation d Cat cells respond to elevated copper by increasing Refrex1 expression d Refrex1 silencing induces cell death by apoptosis in a copper-dependent manner
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hal-04231663 , version 1 (06-10-2023)

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Sandrine Tury, Lise Chauveau, Arnaud Lecante, Valérie Courgnaud, Jean-Luc Battini. A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis. Cell Reports, 2023, 42 (9), pp.113065. ⟨10.1016/j.celrep.2023.113065⟩. ⟨hal-04231663⟩
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