A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis
Résumé
Highlights d Copper transporter CTR1 is the sole receptor for the endogenous retroviral Env Refrex1 d Refrex1 controls CTR1-dependent copper accumulation d Cat cells respond to elevated copper by increasing Refrex1 expression d Refrex1 silencing induces cell death by apoptosis in a copper-dependent manner
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