Introduction: The student population is vulnerable to mental health problems (1–6). The prevalence of post-traumatic stress disorder (PTSD) in the French student population varies between 2.32% (12) to 5.42% (13) but these data need to be updated (12–15). This study aims to revise the data on PTSD in the French student population. Method: Seventy students (70% women; n = 49) participated in a psychometric questionnaire measuring several psychological dimensions. Results: The analyses indicated that 18.5% (n = 13), 24.3% (n = 17) and 20% (n = 14) of the students present severe or very severe intensity scores on the depression, anxiety and stress subscales of the DASS-21. In addition, 18.2% (n = 12) had a PCL-5 score suggestive of PTSD. Discussion: Our results describe major psychological suffering and highlight psychotraumatic issues in the student population. In our article, we discuss the existing treatment protocols in France and abroad that focus on the treatment of PTSD. Conclusion: It is necessary to continue to study the prevalence of PTSD in the student population and to implement treatment plans, resort to the use of peer-help and their interaction with students. It is also essential to adapt the universities’ treatment plans for such students.