Brain-machine interface learning is facilitated by specific patterning of distributed cortical feedback - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Science Advances Année : 2023

Brain-machine interface learning is facilitated by specific patterning of distributed cortical feedback

Résumé

Neuroprosthetics offer great hope for motor-impaired patients. One obstacle is that fine motor control requires near-instantaneous, rich somatosensory feedback. Such distributed feedback may be recreated in a brain-machine interface using distributed artificial stimulation across the cortical surface. Here, we hypothesized that neuronal stimulation must be contiguous in its spatiotemporal dynamics to be efficiently integrated by sensorimotor circuits. Using a closed-loop brain-machine interface, we trained head-fixed mice to control a virtual cursor by modulating the activity of motor cortex neurons. We provided artificial feedback in real time with distributed optogenetic stimulation patterns in the primary somatosensory cortex. Mice developed a specific motor strategy and succeeded to learn the task only when the optogenetic feedback pattern was spatially and temporally contiguous while it moved across the topography of the somatosensory cortex. These results reveal spatiotemporal properties of the sensorimotor cortical integration that set constraints on the design of neuroprosthetics.
Fichier principal
Vignette du fichier
Brain-machine-interface-learning-sciadv-adh1328.pdf (1.24 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-04220009 , version 1 (27-09-2023)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Aamir Abbasi, Henri Lassagne, Luc Estebanez, Dorian Goueytes, Daniel Shulz, et al.. Brain-machine interface learning is facilitated by specific patterning of distributed cortical feedback. Science Advances , 2023, 9 (38), pp.eadh1328. ⟨10.1126/sciadv.adh1328⟩. ⟨hal-04220009⟩
37 Consultations
27 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More