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Article Dans Une Revue Journal of Open Source Software Année : 2023

PAS: a Python Anesthesia Simulator for drug control

Résumé

The Python Anesthesia Simulator (PAS) models the effect of drugs on physiological variables during total intravenous anesthesia. It is particularly dedicated to the control community, to be used as a benchmark for the design of multidrug controllers. The available drugs are propofol, remifentanil, and norepinephrine, the outputs are the bispectral index (BIS), mean arterial pressure (MAP), cardiac output (CO), and tolerance of laryngoscopy (TOL). PAS includes different well-known models along with their uncertainties to simulate inter-patient variability. Blood loss can also be simulated to assess the controller's performance in a shock scenario. Finally, PAS includes standard disturbance profiles and metric computation to facilitate the evaluation of the controller's performance. The statement of need of this package is first discussed; then some pieces of information about the programmed models are provided to the reader. The future developments of the package are discussed at the end.

Domaines

Automatique
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Dates et versions

hal-04183029 , version 1 (18-08-2023)

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Bob Aubouin-Pairault, Thao Dang, Mirko Fiacchini, Mirko Fiacchini, Mirko Fiacchini. PAS: a Python Anesthesia Simulator for drug control. Journal of Open Source Software, 2023, 8 (88), pp.5480. ⟨10.21105/joss.05480⟩. ⟨hal-04183029⟩
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