<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04179873</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-16T20:38:04+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">The Innate Part of the Adaptive Immune System</title>
            <author role="aut">
              <persName>
                <forename type="first">Sophie</forename>
                <surname>Hillion</surname>
              </persName>
              <idno type="halauthorid">682646-0</idno>
              <affiliation ref="#struct-486351"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marina</forename>
                <surname>Arleevskaya</surname>
              </persName>
              <idno type="halauthorid">1508283-0</idno>
              <affiliation ref="#struct-545751"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Patrick</forename>
                <surname>Blanco</surname>
              </persName>
              <idno type="halauthorid">129218-0</idno>
              <affiliation ref="#struct-473693"/>
              <affiliation ref="#struct-300122"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anne</forename>
                <surname>Bordron</surname>
              </persName>
              <email type="md5">27139b74129f07a2b103104d585db4b3</email>
              <email type="domain">univ-brest.fr</email>
              <idno type="idhal" notation="numeric">1534113</idno>
              <idno type="halauthorid" notation="string">682596-1534113</idno>
              <affiliation ref="#struct-486351"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Wesley</forename>
                <surname>Brooks</surname>
              </persName>
              <idno type="halauthorid">900347-0</idno>
              <affiliation ref="#struct-306974"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean Yves</forename>
                <surname>Cesbron</surname>
              </persName>
              <idno type="halauthorid">452815-0</idno>
              <affiliation ref="#struct-459526"/>
              <affiliation ref="#struct-1043050"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Srini</forename>
                <surname>Kaveri</surname>
              </persName>
              <email type="md5">848968a501c9956bc1f94c55fc8fdb25</email>
              <email type="domain">crc.jussieu.fr</email>
              <idno type="idhal" notation="string">srini-kaveri</idno>
              <idno type="idhal" notation="numeric">1178998</idno>
              <idno type="halauthorid" notation="string">1055061-1178998</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0837-4053</idno>
              <affiliation ref="#struct-1004777"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Eric</forename>
                <surname>Vivier</surname>
              </persName>
              <email type="md5">5bfb77e73d4fd86616173673fdef6ee1</email>
              <email type="domain">ciml.univ-mrs.fr</email>
              <idno type="idhal" notation="string">eric-vivier</idno>
              <idno type="idhal" notation="numeric">17342</idno>
              <idno type="halauthorid" notation="string">32004-17342</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/F-8939-2010</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7022-8287</idno>
              <idno type="IDREF">https://www.idref.fr/076121712</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=NlmFOgMAAAAJ</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/F-8939-2010</idno>
              <affiliation ref="#struct-182245"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Yves</forename>
                <surname>Renaudineau</surname>
              </persName>
              <email type="md5">83b01ea38df1d172d66d98607ff2cbba</email>
              <email type="domain">univ-brest.fr</email>
              <idno type="idhal" notation="string">yves-renaudineau</idno>
              <idno type="idhal" notation="numeric">4155</idno>
              <idno type="halauthorid" notation="string">16881-4155</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5098-5002</idno>
              <idno type="ISNI">http://isni.org/isni/0000000140911982</idno>
              <idno type="IDREF">https://www.idref.fr/088747263</idno>
              <affiliation ref="#struct-303644"/>
              <affiliation ref="#struct-486351"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Gisèle</forename>
                <surname>Touzanné</surname>
              </persName>
              <email type="md5">d0e726062c2164a823ab1f00978a8eae</email>
              <email type="domain">chu-toulouse.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2023-08-10 14:58:18</date>
              <date type="whenModified">2026-04-14 07:28:01</date>
              <date type="whenReleased">2023-08-10 14:58:18</date>
              <date type="whenProduced">2020-04</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="1134504">
                <persName>
                  <forename>Gisèle</forename>
                  <surname>Touzanné</surname>
                </persName>
                <email type="md5">d0e726062c2164a823ab1f00978a8eae</email>
                <email type="domain">chu-toulouse.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04179873</idno>
            <idno type="halUri">https://hal.science/hal-04179873</idno>
            <idno type="halBibtex">hillion:hal-04179873</idno>
            <idno type="halRefHtml">&lt;i&gt;Clinical Reviews in Allergy &amp; Immunology&lt;/i&gt;, 2020, 58 (2), pp.151-154. &lt;a target="_blank" href="https://dx.doi.org/10.1007/s12016-019-08740-1"&gt;&amp;#x27E8;10.1007/s12016-019-08740-1&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Clinical Reviews in Allergy &amp; Immunology, 2020, 58 (2), pp.151-154. &amp;#x27E8;10.1007/s12016-019-08740-1&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UNIV-BREST">Université de Bretagne occidentale - Brest (UBO)</idno>
            <idno type="stamp" n="EPHE">École Pratique des Hautes Études</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-AMU">Aix Marseille Université</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="CORDELIERS" corresp="SORBONNE-UNIVERSITE">Centre de recherche des Cordeliers</idno>
            <idno type="stamp" n="IMMUNO" corresp="UNIV-BREST">Lymphocyte B et Auto-immunité, UMR 1227</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="TIMC-IMAG-BNI" corresp="TIMC-IMAG">Barrière Naturelle et Infectiosité</idno>
            <idno type="stamp" n="CERCLE">Publications des lauréats des projets ERC financés sur le site Aix Marseille</idno>
            <idno type="stamp" n="SORBONNE-UNIVERSITE">Sorbonne Université</idno>
            <idno type="stamp" n="SORBONNE-UNIV" corresp="SORBONNE-UNIVERSITE">Sorbonne Université 01/01/2018</idno>
            <idno type="stamp" n="IBSAM" corresp="UNIV-BREST">Institut Brestois Santé Agro Matière</idno>
            <idno type="stamp" n="SU-SCIENCES" corresp="SORBONNE-UNIVERSITE">Faculté des Sciences de Sorbonne Université</idno>
            <idno type="stamp" n="TEST-DEV">TEST-DEV</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UNIVERSITE-PARIS" corresp="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UP-SANTE">Université Paris Cité - Faculté de Santé</idno>
            <idno type="stamp" n="EPHE-PSL" corresp="PSL">École Pratique des Hautes Études - PSL</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="ALLIANCE-SU"> Alliance Sorbonne Université</idno>
            <idno type="stamp" n="NANTES-UNIVERSITE">Nantes Université</idno>
            <idno type="stamp" n="SUPRA_BIOLOGIE">Biologie hors MNHN &amp; stations</idno>
            <idno type="stamp" n="UNIVERSITE-BORDEAUX">Université de Bordeaux</idno>
            <idno type="stamp" n="IMMUNOCONCEPT">Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">The Innate Part of the Adaptive Immune System</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Sophie</forename>
                    <surname>Hillion</surname>
                  </persName>
                  <idno type="halauthorid">682646-0</idno>
                  <affiliation ref="#struct-486351"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marina</forename>
                    <surname>Arleevskaya</surname>
                  </persName>
                  <idno type="halauthorid">1508283-0</idno>
                  <affiliation ref="#struct-545751"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Patrick</forename>
                    <surname>Blanco</surname>
                  </persName>
                  <idno type="halauthorid">129218-0</idno>
                  <affiliation ref="#struct-473693"/>
                  <affiliation ref="#struct-300122"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne</forename>
                    <surname>Bordron</surname>
                  </persName>
                  <email type="md5">27139b74129f07a2b103104d585db4b3</email>
                  <email type="domain">univ-brest.fr</email>
                  <idno type="idhal" notation="numeric">1534113</idno>
                  <idno type="halauthorid" notation="string">682596-1534113</idno>
                  <affiliation ref="#struct-486351"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Wesley</forename>
                    <surname>Brooks</surname>
                  </persName>
                  <idno type="halauthorid">900347-0</idno>
                  <affiliation ref="#struct-306974"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean Yves</forename>
                    <surname>Cesbron</surname>
                  </persName>
                  <idno type="halauthorid">452815-0</idno>
                  <affiliation ref="#struct-459526"/>
                  <affiliation ref="#struct-1043050"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Srini</forename>
                    <surname>Kaveri</surname>
                  </persName>
                  <email type="md5">848968a501c9956bc1f94c55fc8fdb25</email>
                  <email type="domain">crc.jussieu.fr</email>
                  <idno type="idhal" notation="string">srini-kaveri</idno>
                  <idno type="idhal" notation="numeric">1178998</idno>
                  <idno type="halauthorid" notation="string">1055061-1178998</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0837-4053</idno>
                  <affiliation ref="#struct-1004777"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Eric</forename>
                    <surname>Vivier</surname>
                  </persName>
                  <email type="md5">5bfb77e73d4fd86616173673fdef6ee1</email>
                  <email type="domain">ciml.univ-mrs.fr</email>
                  <idno type="idhal" notation="string">eric-vivier</idno>
                  <idno type="idhal" notation="numeric">17342</idno>
                  <idno type="halauthorid" notation="string">32004-17342</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/F-8939-2010</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7022-8287</idno>
                  <idno type="IDREF">https://www.idref.fr/076121712</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=NlmFOgMAAAAJ</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/F-8939-2010</idno>
                  <affiliation ref="#struct-182245"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Yves</forename>
                    <surname>Renaudineau</surname>
                  </persName>
                  <email type="md5">83b01ea38df1d172d66d98607ff2cbba</email>
                  <email type="domain">univ-brest.fr</email>
                  <idno type="idhal" notation="string">yves-renaudineau</idno>
                  <idno type="idhal" notation="numeric">4155</idno>
                  <idno type="halauthorid" notation="string">16881-4155</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5098-5002</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000140911982</idno>
                  <idno type="IDREF">https://www.idref.fr/088747263</idno>
                  <affiliation ref="#struct-303644"/>
                  <affiliation ref="#struct-486351"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">173843</idno>
                <idno type="issn">1559-0267</idno>
                <title level="j">Clinical Reviews in Allergy &amp; Immunology</title>
                <imprint>
                  <publisher>Springer</publisher>
                  <biblScope unit="volume">58</biblScope>
                  <biblScope unit="issue">2</biblScope>
                  <biblScope unit="pp">151-154</biblScope>
                  <date type="datePub">2020-04</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1007/s12016-019-08740-1</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Complement</term>
                <term xml:lang="en">Adaptive immunity</term>
                <term xml:lang="en">Antibody</term>
                <term xml:lang="en">Innate immunity</term>
                <term xml:lang="en">Lymphocytes</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>The innate immune response provides a first line of defense against common microorganisms and, for more complex and/or recurring situations where pathogens must be eliminated, an adaptive immune response has emerged and evolved to provide better protection against subsequent infections. However, such dichotomy has to be reevaluated because innate B cells (e.g., B1 and marginal zone B cells) and the newly described innate lymphoid cells (iLC) have been found to exhibit innate-like properties, such as antigen internalization, regulatory B cell functions, and helper T cell activities. In addition, the production and function of natural antibodies (nAbs) by innate B cells and their capacity to activate the classical complement pathway constitute additional important mechanisms at the junction of innate and adaptive immunity as well as the recent integration of platelets into the innate immune spectrum. There is no doubt that these mechanisms present an advantage in immunity and homeostasis particularly during the first years of life, but arguments are arising to consider that these precursors may have detrimental effects in a variety of autoimmune/inflammatory diseases, allergies and cancers, as well as in response to immunotherapy. Accordingly, and as presented in this special issue of Clinical Reviews in Allergy and Immunology, a better comprehension of the key molecular and cellular actors implicated at the crossroads of the innate and adaptive immune response represents a new challenge in our understanding of the immunological and immunopathological responses.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-486351" status="VALID">
          <idno type="RNSR">201722606C</idno>
          <orgName>Lymphocytes B, Autoimmunité et Immunothérapies</orgName>
          <orgName type="acronym">LBAI</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <addrLine>5 Foch - CHU Morvan - BP 824 - 29609 Brest - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://nouveau.univ-brest.fr/lbai/fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300314" type="direct"/>
            <relation name="U1227" active="#struct-303623" type="direct"/>
            <relation active="#struct-303644" type="direct"/>
            <relation active="#struct-1083366" type="indirect"/>
            <relation active="#struct-519898" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-545751" status="VALID">
          <idno type="ROR">https://ror.org/05256ym39</idno>
          <orgName>Kazan Federal University</orgName>
          <orgName type="acronym">KFU</orgName>
          <date type="start">1804-01-01</date>
          <desc>
            <address>
              <addrLine>18 Kremlyovskaya street, Kazan 420008</addrLine>
              <country key="RU"/>
            </address>
            <ref type="url">https://kpfu.ru/eng</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-473693" status="VALID">
          <idno type="IdRef">184704715</idno>
          <idno type="ISNI">0000000403830819</idno>
          <idno type="RNSR">200311838J</idno>
          <idno type="ROR">https://ror.org/02dsacc67</idno>
          <orgName>Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle</orgName>
          <orgName type="acronym">ImmunoConcept</orgName>
          <date type="start">2003-01-01</date>
          <desc>
            <address>
              <addrLine>146, rue Léo Saignat - 33076 Bordeaux Cedex - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.immuconcept.org/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-259761" type="direct"/>
            <relation name="ERL 1303" active="#struct-303623" type="direct"/>
            <relation name="UMR5164" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300122" status="VALID">
          <idno type="IdRef">028228421</idno>
          <idno type="ROR">https://ror.org/01hq89f96</idno>
          <orgName>Centre Hospitalier Universitaire de Bordeaux</orgName>
          <orgName type="acronym">CHU Bordeaux</orgName>
          <desc>
            <address>
              <addrLine>12 rue Dubernat 33400 Talence</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-bordeaux.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306974" status="VALID">
          <idno type="ROR">https://ror.org/032db5x82</idno>
          <orgName>University of South Florida [Tampa]</orgName>
          <orgName type="acronym">USF</orgName>
          <desc>
            <address>
              <addrLine>4202 E. Fowler Avenue,  Tampa, FL 33620, USA</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">https://www.usf.edu/</ref>
          </desc>
        </org>
        <org type="department" xml:id="struct-459526" status="OLD">
          <orgName>Service d'immunologie [CHU Grenoble]</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-257328" type="direct"/>
          </listRelation>
        </org>
        <org type="researchteam" xml:id="struct-1043050" status="OLD">
          <orgName>Barrière Naturelle et Infectiosité</orgName>
          <orgName type="acronym">TIMC-IMAG-BNI</orgName>
          <date type="start">2020-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr/BNI</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1070489" type="direct"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
            <relation active="#struct-1042703" type="indirect"/>
            <relation active="#struct-1043329" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1004777" status="VALID">
          <idno type="IdRef">158039203</idno>
          <idno type="ISNI">0000 0004 0620 5824 </idno>
          <idno type="RNSR">200716512X</idno>
          <orgName>Centre de Recherche des Cordeliers</orgName>
          <orgName type="acronym">CRC (UMR_S_1138 / U1138)</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>15 rue de l'Ecole de Médecine - Bâtiment B - 75270 Paris Cedex 06</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.crc.jussieu.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-110691" type="direct"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation name="U1138" active="#struct-303623" type="direct"/>
            <relation active="#struct-413221" type="direct"/>
            <relation name="UMR_S_1138" active="#struct-557826" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-182245" status="VALID">
          <idno type="IdRef">150044909</idno>
          <idno type="RNSR">200017461J</idno>
          <idno type="ROR">03vyjkj45</idno>
          <orgName>Centre d'Immunologie de Marseille - Luminy</orgName>
          <orgName type="acronym">CIML</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Parc scientifique et technologique de Luminy - 163, avenue de Luminy - Case 906 - 13288 Marseille cedex 09</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UM 2" active="#struct-198056" type="direct"/>
            <relation name="UMR_S 1104" active="#struct-303623" type="direct"/>
            <relation name="UMR7280" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-303644" status="VALID">
          <orgName>LabEX IGO Immunothérapie Grand Ouest</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-1083366" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300314" status="VALID">
          <idno type="IdRef">291809022</idno>
          <idno type="ISNI">0000000121880893</idno>
          <idno type="ROR">https://ror.org/0372th171</idno>
          <orgName>Université de Brest</orgName>
          <orgName type="acronym">UBO EPE</orgName>
          <desc>
            <address>
              <addrLine>Université de Bretagne Occidentale - 3 Rue des Archives 29238, Brest</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-brest.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1083366" status="VALID">
          <idno type="IdRef">258086599</idno>
          <idno type="ROR">https://ror.org/03gnr7b55</idno>
          <orgName>Nantes Université</orgName>
          <orgName type="acronym">Nantes Univ</orgName>
          <date type="start">2022-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-519898" status="VALID">
          <idno type="RNSR">201722456P</idno>
          <orgName>Institut Brestois Santé Agro Matière</orgName>
          <orgName type="acronym">IBSAM</orgName>
          <date type="start">2017-10-12</date>
          <desc>
            <address>
              <addrLine>Université de Brest- UBO29238 Brest</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-brest.fr/menu/recherche-innovation/Laboratoires/Axe+Sant%C3%A9-+Agro-+Mati%C3%A8re/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300314" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-259761" status="VALID">
          <idno type="IdRef">175206562</idno>
          <idno type="ROR">https://ror.org/057qpr032</idno>
          <orgName>Université de Bordeaux</orgName>
          <orgName type="acronym">UB</orgName>
          <desc>
            <address>
              <addrLine>35, place Pey Berland - 33076 Bordeaux</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-bordeaux.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-257328" status="VALID">
          <idno type="IdRef">034137076</idno>
          <idno type="ROR">https://ror.org/041rhpw39</idno>
          <orgName>CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble</orgName>
          <orgName type="acronym">CHUGA</orgName>
          <desc>
            <address>
              <addrLine>CS 1021738043 Grenoble cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-1070489" status="OLD">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble - UMR 5525</orgName>
          <orgName type="acronym">TIMC-IMAG</orgName>
          <date type="start">2020-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.timc.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
            <relation active="#struct-1042703" type="direct"/>
            <relation active="#struct-1043329" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1043329" status="VALID">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1042703" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-110691" status="VALID">
          <idno type="IdRef">026375478</idno>
          <idno type="ISNI">0000000121955365</idno>
          <idno type="ROR">https://ror.org/046b3cj80</idno>
          <orgName>École Pratique des Hautes Études</orgName>
          <orgName type="acronym">EPHE</orgName>
          <date type="start">1868-01-01</date>
          <desc>
            <address>
              <addrLine>4-14 Rue Ferrus, 75014 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ephe.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-564132" status="VALID">
          <idno type="IdRef">241597595</idno>
          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-413221" status="VALID">
          <idno type="IdRef">221333754</idno>
          <idno type="ROR">https://ror.org/02en5vm52</idno>
          <orgName>Sorbonne Université</orgName>
          <orgName type="acronym">SU</orgName>
          <date type="start">2018-01-01</date>
          <desc>
            <address>
              <addrLine>21 rue de l’École de médecine - 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-universite.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-557826" status="VALID">
          <idno type="IdRef">236453505</idno>
          <idno type="ISNI">0000 0004 7885 7602</idno>
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris Cité</orgName>
          <orgName type="acronym">UPCité</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>85 boulevard Saint-Germain75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://u-paris.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-198056" status="VALID">
          <idno type="IdRef">15863621X</idno>
          <idno type="ISNI">0000 0001 2176 4817</idno>
          <idno type="ROR">https://ror.org/035xkbk20</idno>
          <orgName>Aix Marseille Université</orgName>
          <orgName type="acronym">AMU</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-amu.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>