Robust associations between genetic traits and neurodegenerative pathologies have been established thanks to the advent of GWAS. Meta-analysis incorporating tens of thousands of subjects allowed to discover hundreds of genetic loci associated with the diagnosis of diseases such as Alzheimer's Disease. Our aim is to identify associations between SNPs and longitudinal features of the disease progression, such as speed of progression, feature-specific dynamic patterns, etc. A finer understanding of the link between SNPs and disease progression could help design new polygenic risk scores, targeting not the diagnosis, but rather for instance progression speed, hence allowing for higher-powered clinical trials for instance.