The Web and social media have become the main source of information for citizens, with the risk that users rely on shallow information in sources prioritizing commercial or political incentives rather than the correctness and informational value. Non-experts tend to avoid scientific literature due to its complex language or their lack of prior background knowledge. Text simplification promises to remove some of these barriers. The CLEF 2022 SimpleText track addresses the challenges of text simplification approaches in the context of promoting scientific information access, by providing appropriate data and benchmarks, and creating a community of NLP and IR researchers working together to resolve one of the greatest challenges of today. The track will use a corpus of scientific literature abstracts and popular science requests. It features three tasks. First, content selection (what is in, or out?) challenges systems to select passages to include in a simplified summary in response to a query. Second, complexity spotting (what is unclear?) given a passage and a query, aims to rank terms/concepts that are required to be explained for understanding this passage (definitions, context, applications). Third, text simplification (rewrite this!) given a query, asks to simplify passages from scientific abstracts while preserving the main content.