Multifaceted functions of histone deacetylases in stress response - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Trends in Plant Science Année : 2023

Multifaceted functions of histone deacetylases in stress response

Résumé

Chromatin remodeling is the dynamic modification of chromatin architecture by ATPdependent chromatin remodeling proteins complexes. These complexes recognize chromatin modifications such histone acetylation, control chromatin states between relaxation and condensation, and thus regulate gene activity. Histone lysine acylations mirror acetylation, but entail histone acylation of histone lysine residues with either short-chain fatty acids, such as malonylation (Kmal), propionylation (Kpr), butyrylation (Kbu), crotonylation (Kcr), β-hydroxybutyrylation (Kbhb), 2-hydroxyisobutyrylation (Khib), or dicarboxylic acids such as succinylation (Ksu). HAT and HDAC are involved in lysine acylation and deacylation. Post-translational modification (PTM) is the covalent modification of proteins following protein biosynthesis by ribosomes. As an example, phosphorylation is adding a phosphate to a hydroxyl group of an amino acid residue. Among other types of PTMs are ubiquitination, acetylation or Snitrosylation. PTMs usually respond to cell signaling and regulate the modified protein function. Stress granules are dense aggregations composed of proteins and RNAs that can appear in different cell compartments when the cell is under stress.
Fichier principal
Vignette du fichier
Cui et al 2023.pdf (514.28 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04155434 , version 1 (07-07-2023)

Identifiants

Citer

Xiaoyun Cui, Avilien Dard, Jean-Philippe Reichheld, Dao-Xiu Zhou. Multifaceted functions of histone deacetylases in stress response. Trends in Plant Science, inPress, ⟨10.1016/j.tplants.2023.06.006⟩. ⟨hal-04155434⟩
41 Consultations
79 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More