<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04134585</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-16T21:52:34+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Intensive Multimodal Treatment for A Young Adult with Friedreich Ataxia: A Case Report</title>
            <author role="aut">
              <persName>
                <forename type="first">Grace</forename>
                <surname>Battal</surname>
              </persName>
              <idno type="halauthorid">2841273-0</idno>
              <affiliation ref="#struct-303340"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nicolas</forename>
                <surname>Pinsault</surname>
              </persName>
              <email type="md5">b8eaab24400323dae71563c9849fb070</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
              <idno type="idhal" notation="string">nicolas-pinsault</idno>
              <idno type="idhal" notation="numeric">172272</idno>
              <idno type="halauthorid" notation="string">4632-172272</idno>
              <idno type="IDREF">https://www.idref.fr/138493782</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5034-0802</idno>
              <idno type="VIAF">https://viaf.org/viaf/191926980</idno>
              <idno type="ISNI">http://isni.org/isni/0000000356805871</idno>
              <affiliation ref="#struct-1043060"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Berthe</forename>
                <surname>Hanna-Boutros</surname>
              </persName>
              <idno type="halauthorid">892598-0</idno>
              <affiliation ref="#struct-303340"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Nicolas</forename>
                <surname>PINSAULT</surname>
              </persName>
              <email type="md5">b8eaab24400323dae71563c9849fb070</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2023-06-20 15:07:39</date>
              <date type="whenModified">2025-09-27 19:10:29</date>
              <date type="whenReleased">2023-06-20 18:42:38</date>
              <date type="whenProduced">2023</date>
              <date type="whenEndEmbargoed">2023-06-20</date>
              <ref type="file" target="https://hal.science/hal-04134585v1/document">
                <date notBefore="2023-06-20"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://hal.science/hal-04134585v1/file/IJPR.2023.110.pdf" id="file-4134585-3600063">
                <date notBefore="2023-06-20"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="697103">
                <persName>
                  <forename>Nicolas</forename>
                  <surname>PINSAULT</surname>
                </persName>
                <email type="md5">b8eaab24400323dae71563c9849fb070</email>
                <email type="domain">univ-grenoble-alpes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04134585</idno>
            <idno type="halUri">https://hal.science/hal-04134585</idno>
            <idno type="halBibtex">battal:hal-04134585</idno>
            <idno type="halRefHtml">&lt;i&gt;International Journal of Physiotherapy and Research&lt;/i&gt;, 2023, 11 (3), pp.4508-4516. &lt;a target="_blank" href="https://dx.doi.org/10.16965/ijpr.2023.110"&gt;&amp;#x27E8;10.16965/ijpr.2023.110&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">International Journal of Physiotherapy and Research, 2023, 11 (3), pp.4508-4516. &amp;#x27E8;10.16965/ijpr.2023.110&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-4134585-3600063"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-THEMAS" corresp="TIMC-IMAG">ThEMAS : Techniques pour l'Evaluation et la Modélisation des Actions de Santé</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Intensive Multimodal Treatment for A Young Adult with Friedreich Ataxia: A Case Report</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Grace</forename>
                    <surname>Battal</surname>
                  </persName>
                  <idno type="halauthorid">2841273-0</idno>
                  <affiliation ref="#struct-303340"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nicolas</forename>
                    <surname>Pinsault</surname>
                  </persName>
                  <email type="md5">b8eaab24400323dae71563c9849fb070</email>
                  <email type="domain">univ-grenoble-alpes.fr</email>
                  <idno type="idhal" notation="string">nicolas-pinsault</idno>
                  <idno type="idhal" notation="numeric">172272</idno>
                  <idno type="halauthorid" notation="string">4632-172272</idno>
                  <idno type="IDREF">https://www.idref.fr/138493782</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5034-0802</idno>
                  <idno type="VIAF">https://viaf.org/viaf/191926980</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000356805871</idno>
                  <affiliation ref="#struct-1043060"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Berthe</forename>
                    <surname>Hanna-Boutros</surname>
                  </persName>
                  <idno type="halauthorid">892598-0</idno>
                  <affiliation ref="#struct-303340"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="INCOMING">564787</idno>
                <idno type="issn">2321-8975</idno>
                <title level="j">International Journal of Physiotherapy and Research</title>
                <imprint>
                  <biblScope unit="volume">11</biblScope>
                  <biblScope unit="issue">3</biblScope>
                  <biblScope unit="pp">4508-4516</biblScope>
                  <date type="datePub">2023</date>
                </imprint>
              </monogr>
              <idno type="doi">10.16965/ijpr.2023.110</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Friedreich's ataxia</term>
                <term xml:lang="en">Rehabilitation outcomes</term>
                <term xml:lang="en">Physical therapy</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.mhep.phy">Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]</classCode>
              <classCode scheme="halDomain" n="sdv.neu">Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Background: Friedreich’s ataxia (FRDA) is a progressive, neurodegenerative autosomal recessive disorder affecting multiple systems of the body. Physical therapy has been found to be beneficial for improving function and quality of life in individuals with FRDA. However, there is little evidence supporting specific interventions that would address functional concerns in these patients, and the most optimal rehabilitation strategy has yet to be determined.Case Presentation: The participant was a twenty-six-year-old female who had been diagnosed with FRDA ten years earlier. After discontinuing physical therapy for three years, she started using a wheelchair and her function declined. The primary outcome measures employed to assess FRDA were the scale for assessment and rating of ataxia (SARA) and the functional independence measure (FIM). Other measures included strength, range of motion and neurologic screening. At initial examination, the participant presented with muscle weakness, poor balance and coordination, and mobility restrictions. The patient received intensive physical therapy with five weekly sessions over a period of three months. Interventions focused on coordinative, balance, and strength training activities.Results: The patient demonstrated a 30-point increase in the FIM, a 9-point decrease in the SARA, and amelioration in manual muscle testing scores upon completion of the rehabilitation program.Conclusion: The FRDA patient displayed improvement in all outcome measures. Strength, ataxia severity and functional abilities were enhanced while a higher level of independence was gained. Our observations suggest that an intensive multimodal approach holds potential in the management of FRDA and call for further research.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="institution" xml:id="struct-303340" status="VALID">
          <idno type="IdRef">08401430X</idno>
          <idno type="ISNI">0000 0001 2324 3572</idno>
          <idno type="ROR">https://ror.org/05x6qnc69</idno>
          <idno type="Wikidata">Q975461</idno>
          <orgName>الجامعة اللبنانية [بيروت] = Lebanese University [Beirut] = Université libanaise [Beyrouth]</orgName>
          <orgName type="acronym">LU / ULB</orgName>
          <date type="start">1951-01-01</date>
          <desc>
            <address>
              <addrLine>P.O. Box 6573/14 Badaro, Museum, Beirut</addrLine>
              <country key="LB"/>
            </address>
            <ref type="url">https://www.ul.edu.lb/</ref>
          </desc>
        </org>
        <org type="researchteam" xml:id="struct-1043060" status="VALID">
          <orgName>Techniques pour l'Evaluation et la Modélisation des Actions de la Santé</orgName>
          <orgName type="acronym">TIMC-ThEMAS</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.timc.fr/themas</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1043049" type="direct"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
            <relation active="#struct-1042703" type="indirect"/>
            <relation active="#struct-1043329" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1043049" status="VALID">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525</orgName>
          <orgName type="acronym">TIMC</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.timc.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
            <relation active="#struct-1042703" type="direct"/>
            <relation active="#struct-1043329" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1043329" status="VALID">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1042703" type="direct"/>
          </listRelation>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>