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            <funder>Société Nationale Française de Gastro-Entérologie, SNFGE; Société de Pneumologie de Langue Française, SPLF</funder>
            <funder>We would like to thank the Société de Pneumologie de Langue Française (SPLF), the Société Française d'Oto-Rhino-Laryngologie et de Chirurgie de la Face et du Cou (SFORL), the Société Française de Phoniatrie et de Laryngologie (SFPL), the Société Nationale Française de Gastro-entérologie (SNFGE) for providing their support on these guidelines. We also acknowledge the independent review of the following group: Olivier Cantal, Guillaume De Bonnecaze, Roger Escamilla, François Kermich, Mathieu Larousse, Christophe Leroyer, Franck Marmouset, Laurent Portel, Nicolas Roche, Philippe Schultz, and Franck Zerbib</funder>
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                <term xml:lang="en">Chronic cough</term>
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              <p>Patients with chronic cough experience a high alteration of quality of life. Moreover, chronic cough is a complex entity with numerous etiologies and treatments. In order to help clinicians involved in the management of patients with chronic cough, guidelines on chronic cough have been established by a group of French experts. These guidelines address the definitions of chronic cough and the initial management of patients with chronic cough. We present herein second-line tests that might be considered in patients with cough persistence despite initial management. Experts also propose a definition of unexplained or refractory chronic cough (URCC) in order to better identify patients whose cough persists despite optimal management. Finally, these guidelines address the pharmacological and non-pharmacological interventions useful in URCC. Thus, amitryptilline, pregabalin, gabapentin or morphine combined with speech and/or physical therapy are a mainstay of treatment strategies in URCC. Other treatment options, such as P2 × 3 antagonists, are being developed.</p>
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