Widening the landscape of transcriptional regulation of green algal photoprotection - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Nature Communications Année : 2023

Widening the landscape of transcriptional regulation of green algal photoprotection

Résumé

Abstract Availability of light and CO 2 , substrates of microalgae photosynthesis, is frequently far from optimal. Microalgae activate photoprotection under strong light, to prevent oxidative damage, and the CO 2 Concentrating Mechanism (CCM) under low CO 2 , to raise intracellular CO 2 levels. The two processes are interconnected; yet, the underlying transcriptional regulators remain largely unknown. Employing a large transcriptomic data compendium of Chlamydomonas reinhardtii’s responses to different light and carbon supply, we reconstruct a consensus genome-scale gene regulatory network from complementary inference approaches and use it to elucidate transcriptional regulators of photoprotection. We show that the CCM regulator LCR1 also controls photoprotection, and that QER7, a Squamosa Binding Protein, suppresses photoprotection- and CCM-gene expression under the control of the blue light photoreceptor Phototropin. By demonstrating the existence of regulatory hubs that channel light- and CO 2 -mediated signals into a common response, our study provides an accessible resource to dissect gene expression regulation in this microalga.
Fichier principal
Vignette du fichier
Arend-2023-Widening the landsca.pdf (1.5 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-04097825 , version 1 (15-05-2023)

Licence

Paternité

Identifiants

Citer

Marius Arend, Yizhong Yuan, M Águila Ruiz-Sola, Nooshin Omranian, Zoran Nikoloski, et al.. Widening the landscape of transcriptional regulation of green algal photoprotection. Nature Communications, 2023, 14 (1), pp.2687. ⟨10.1038/s41467-023-38183-4⟩. ⟨hal-04097825⟩
35 Consultations
28 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More