Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes - Archive ouverte HAL Access content directly
Journal Articles (Data Paper) Cell Genomics Year : 2023

Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes

Albert J Poustka
  • Function : Author
Cinta Pegueroles
  • Function : Author
Marco Borra
  • Function : Author
Elijah K Lowe
  • Function : Author
Guy Lhomond
  • Function : Author
Lydia Besnardeau
  • Function : Author
Daria Gavriouchkina
  • Function : Author
Roberta Russo
  • Function : Author
Caterina Costa
  • Function : Author
Francesca Zito
  • Function : Author
Letizia Anello
  • Function : Author
Aldo Nicosia
  • Function : Author
Maria Antonietta Ragusa
  • Function : Author
Marta Pascual
  • Function : Author
Marta Di Carlo
  • Function : Author
Xavier Turon
  • Function : Author
Richard R Copley
  • Function : Author
Pedro Martinez
  • Function : Author
Vincenzo Cavalieri
  • Function : Author
Smadar Ben Tabou de Leon
  • Function : Author
Jenifer Croce
  • Function : Author
Paola Oliveri
  • Function : Author
Valeria Matranga
  • Function : Author
Maria Di Bernardo
  • Function : Author
Julia Morales
  • Function : Author
Jean Marc Aury
  • Function : Author
Valérie Barbe
  • Function : Author
Patrick Wincker
  • Function : Author
Maria Ina Arnone
  • Function : Author
Thierry Lepage
  • Function : Author
  • PersonId : 1253065

Abstract

Sea urchins are emblematic models in developmental biology and display several characteristics that set them apart from other deuterostomes. To uncover the genomic cues that may underlie these specificities, we generated a chromosome-scale genome assembly for the sea urchin Paracentrotus lividus and an extensive gene expression and epigenetic profiles of its embryonic development. We found that, unlike vertebrates, sea urchins retained ancestral chromosomal linkages but underwent very fast intrachromosomal gene order mixing. We identified a burst of gene duplication in the echinoid lineage and showed that some of these expanded genes have been recruited in novel structures (water vascular system, Aristotle’s lantern, and skeletogenic micromere lineage). Finally, we identified gene-regulatory modules conserved between sea urchins and chordates. Our results suggest that gene-regulatory networks controlling development can be conserved despite extensive gene order rearrangement.
Fichier principal
Vignette du fichier
2023_GenomePlividusR.pdf (7.11 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive

Dates and versions

hal-04093287 , version 1 (10-05-2023)

Identifiers

Cite

Ferdinand Marlétaz, Arnaud Couloux, Julie Poulain, Karine Labadie, Corinne da Silva, et al.. Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes. Cell Genomics, 2023, 3 (4), pp.100295. ⟨10.1016/j.xgen.2023.100295⟩. ⟨hal-04093287⟩
11 View
4 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More