Genomics of the ccoNOQP -encoded cbb 3 oxidase complex in bacteria - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Archives of Microbiology Année : 2004

Genomics of the ccoNOQP -encoded cbb 3 oxidase complex in bacteria

Résumé

Many bacteria adapt to microoxic conditions by synthesizing a particular cytochrome c oxidase (cbb 3) complex with a high affinity for O2, encoded by the ccoNOQP operon. A survey of genome databases indicates that ccoNOQP sequences are widespread in all sub-branches of Proteobacteria but otherwise are found only in bacteria of the CFB group (Cytophaga, Flexibacter, Bacteroides). Our analysis of available genome sequences suggests four major strategies of regulating ccoNOQP expression in response to O2. The most widespread strategy involves direct regulation by the O2-responsive protein Fnr. The second strategy involves an O2-insensitive paralogue of Fnr, FixK, whose expression is regulated by the O2-responding FixLJ two-component system. A third strategy of mixed regulation operates in bacteria carrying both fnr and fixLJ-fixK genes. Another, not yet identified, strategy is likely to operate in the ε-Proteobacteria Helicobacter pylori and Campylobacter jejuni which lack fnr and fixLJ-fixK genes. The FixLJ strategy appears specific for the α-subclass of Proteobacteria but is not restricted to rhizobia in which it was originally discovered.

Dates et versions

hal-04088931 , version 1 (04-05-2023)

Licence

Copyright (Tous droits réservés)

Identifiants

Citer

Jacques Batut, Celine Cosseau. Genomics of the ccoNOQP -encoded cbb 3 oxidase complex in bacteria. Archives of Microbiology, 2004, 181 (2), pp.89-96. ⟨10.1007/s00203-003-0641-5⟩. ⟨hal-04088931⟩
9 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More