SO 2 -Extrusive 1,4-(Het)Aryl Migration: Synthesis of α-Aryl Amides and Related Reactions - Archive ouverte HAL
Article Dans Une Revue Synthesis: Journal of Synthetic Organic Chemistry Année : 2022

SO 2 -Extrusive 1,4-(Het)Aryl Migration: Synthesis of α-Aryl Amides and Related Reactions

Résumé

(Het)Aryl migration has emerged as a key synthetic tool and has particularly been exploited for the synthesis of α-aryl amides. This method overcomes the existing α-arylation methods, which are not always compatible with the introduction of (het)aryl groups possessing bulky or electrophilic substituents. This review focuses on SO2-extrusive (het)aryl migration in the frame of α-aryl amide synthesis. Anion-and radicalmediated transformations are reported including the synthesis of polycyclic compounds through cascade reactions. 1 Introduction 2 Anionic aryl migration 3 Radical aryl migration 4 Conclusion

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Chimie
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Dates et versions

hal-04076896 , version 1 (21-04-2023)

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Nicolas G.-Simonian, Amandine Guérinot, Janine Cossy. SO 2 -Extrusive 1,4-(Het)Aryl Migration: Synthesis of α-Aryl Amides and Related Reactions. Synthesis: Journal of Synthetic Organic Chemistry, 2022, ⟨10.1055/s-0040-1720035⟩. ⟨hal-04076896⟩
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