<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04062159</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-16T23:59:02+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries</title>
            <author role="crp">
              <persName>
                <forename type="first">Manon</forename>
                <surname>Lesage</surname>
              </persName>
              <email type="md5">642c637c80b50104b97802ff83128b38</email>
              <email type="domain">inrae.fr</email>
              <idno type="idhal" notation="string">manon-lesage</idno>
              <idno type="idhal" notation="numeric">743015</idno>
              <idno type="halauthorid" notation="string">50105-743015</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3121-5181</idno>
              <affiliation ref="#struct-1002344"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Manon</forename>
                <surname>Thomas</surname>
              </persName>
              <email type="md5">5b7f62a7ddde6ae82b17c36820ce44d7</email>
              <email type="domain">inrae.fr</email>
              <idno type="idhal" notation="string">manon-thomas</idno>
              <idno type="idhal" notation="numeric">741968</idno>
              <idno type="halauthorid" notation="string">50106-741968</idno>
              <affiliation ref="#struct-1002344"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Thierry</forename>
                <surname>Pécot</surname>
              </persName>
              <email type="md5">41a8830d6d3734601b1826344aa875f6</email>
              <email type="domain">univ-rennes1.fr</email>
              <idno type="idhal" notation="numeric">1128783</idno>
              <idno type="halauthorid" notation="string">786684-1128783</idno>
              <affiliation ref="#struct-453207"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Tu-Ky</forename>
                <surname>Ly</surname>
              </persName>
              <email type="md5">52a99a4fbd3be451b51a1a7f203d1b61</email>
              <email type="domain">gmail.com</email>
              <idno type="idhal" notation="string">tuky-ly</idno>
              <idno type="idhal" notation="numeric">1502622</idno>
              <idno type="halauthorid" notation="string">2755960-1502622</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-4112-5312</idno>
              <affiliation ref="#struct-3186"/>
              <affiliation ref="#struct-254401"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nathalie</forename>
                <surname>Hinfray</surname>
              </persName>
              <email type="md5">5de05b0ad6f226590a88f7a4b1d4d0e2</email>
              <email type="domain">ineris.fr</email>
              <idno type="idhal" notation="string">nathalie-hinfray</idno>
              <idno type="idhal" notation="numeric">1011043</idno>
              <idno type="halauthorid" notation="string">201055-1011043</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/Q-6625-2018</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-3887-6043</idno>
              <affiliation ref="#struct-3186"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Rémy</forename>
                <surname>Beaudouin</surname>
              </persName>
              <email type="md5">c3d7e34f16198007c25ccdcd34ad22a7</email>
              <email type="domain">ineris.fr</email>
              <idno type="idhal" notation="string">remybeaudouin</idno>
              <idno type="idhal" notation="numeric">754091</idno>
              <idno type="halauthorid" notation="string">38407-754091</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/H-1491-2012</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-2855-1571</idno>
              <idno type="IDREF">https://www.idref.fr/12234071X</idno>
              <affiliation ref="#struct-3186"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michelle</forename>
                <surname>Neumann</surname>
              </persName>
              <idno type="halauthorid">2781008-0</idno>
              <affiliation ref="#struct-442033"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Robin</forename>
                <surname>Lovell-Badge</surname>
              </persName>
              <email type="md5">0497d8cd440e12e4e04aee44a640b1a8</email>
              <email type="domain">crick.ac.uk</email>
              <idno type="idhal" notation="numeric">1153855</idno>
              <idno type="halauthorid" notation="string">546886-1153855</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9364-4179</idno>
              <affiliation ref="#struct-442033"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jérôme</forename>
                <surname>Bugeon</surname>
              </persName>
              <email type="md5">564a68025046287b3005cc370b11acc8</email>
              <email type="domain">inrae.fr</email>
              <idno type="idhal" notation="string">jerome-bugeon</idno>
              <idno type="idhal" notation="numeric">739227</idno>
              <idno type="halauthorid" notation="string">48032-739227</idno>
              <idno type="IDREF">https://www.idref.fr/059683171</idno>
              <idno type="ORCID">https://orcid.org/0009-0005-2042-3953</idno>
              <affiliation ref="#struct-1002344"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">Violette</forename>
                <surname>Thermes</surname>
              </persName>
              <email type="md5">94326621fb84b2e3d546db2bf28ec3a3</email>
              <email type="domain">inrae.fr</email>
              <idno type="idhal" notation="string">violette-thermes</idno>
              <idno type="idhal" notation="numeric">738713</idno>
              <idno type="halauthorid" notation="string">48036-738713</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0838-4155</idno>
              <idno type="IDREF">https://www.idref.fr/088810062</idno>
              <affiliation ref="#struct-1002344"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Laurent</forename>
                <surname>Jonchère</surname>
              </persName>
              <email type="md5">dc1f1e9bdb3dc2065f8bf1bfd5663118</email>
              <email type="domain">univ-rennes.fr</email>
            </editor>
            <funder ref="#projanr-48334"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2023-04-07 12:59:40</date>
              <date type="whenModified">2025-06-24 10:24:29</date>
              <date type="whenReleased">2023-04-07 12:59:40</date>
              <date type="whenProduced">2023-03-27</date>
              <ref type="externalLink" target="https://journals.biologists.com/dev/article-pdf/150/7/dev201185/2780589/dev201185.pdf"/>
              <fs>
                <f name="inra_etatDocument_local" notation="numeric">
                  <numeric>0</numeric>
                </f>
                <f name="inra_etatDocument_local" notation="string" n="0">
                  <string>inra_etatDocument_local_0</string>
                </f>
                <f name="inra_publicVise_local" notation="string" n="SC">
                  <string>inra_publicVise_local_SC</string>
                </f>
              </fs>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="113861">
                <persName>
                  <forename>Laurent</forename>
                  <surname>Jonchère</surname>
                </persName>
                <email type="md5">dc1f1e9bdb3dc2065f8bf1bfd5663118</email>
                <email type="domain">univ-rennes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04062159</idno>
            <idno type="halUri">https://hal.science/hal-04062159</idno>
            <idno type="halBibtex">lesage:hal-04062159</idno>
            <idno type="halRefHtml">&lt;i&gt;Development (Cambridge, England)&lt;/i&gt;, 2023, 150 (7), pp.dev201185. &lt;a target="_blank" href="https://dx.doi.org/10.1242/dev.201185"&gt;&amp;#x27E8;10.1242/dev.201185&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Development (Cambridge, England), 2023, 150 (7), pp.dev201185. &amp;#x27E8;10.1242/dev.201185&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INERIS">INERIS - Institut National de l'Environnement industriel et des RISques</idno>
            <idno type="stamp" n="UNIV-RENNES1">Université de Rennes 1</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="URCA">Publications de l'Université de Reims Champagne-Ardenne</idno>
            <idno type="stamp" n="IFR140">SFR Biosit - Biologie et Santé CNRS UMS 3480</idno>
            <idno type="stamp" n="STATS-UR1">Statistiques-HAL-UR1</idno>
            <idno type="stamp" n="BIOSIT">SFR Biosit - Biologie et Santé CNRS UMS 3480</idno>
            <idno type="stamp" n="COMUE-NORMANDIE">Normandie Université</idno>
            <idno type="stamp" n="LPGP"> Laboratoire de Physiologie et Génomique des Poissons Inra UR 1037</idno>
            <idno type="stamp" n="UR1-HAL">Publications labos UR1 dans HAL-Rennes 1</idno>
            <idno type="stamp" n="UR1-SDV">UR1 - publications SDV</idno>
            <idno type="stamp" n="SEBIO" corresp="URCA">Stress Environnementaux et BIOsurveillance des milieux aquatiques - UMR-I 02</idno>
            <idno type="stamp" n="TEST-UR-CSS">TEST Université de Rennes CSS</idno>
            <idno type="stamp" n="UNIV-RENNES">Université de Rennes</idno>
            <idno type="stamp" n="UNILEHAVRE">Université Le Havre Normandie</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="INSTITUT-SCIENCES-LUMIERE">Institut des Sciences de la Lumière</idno>
            <idno type="stamp" n="PHASE">Physiologie animale et systèmes d’élevage</idno>
            <idno type="stamp" n="DIGIT-BIO">Métaprogramme DIGIT-BIO "Biologie numérique pour explorer et prédire le vivant"</idno>
            <idno type="stamp" n="ANR-OCEANS-15TO18" corresp="ANR-OCEANS">ANR-OCEANS-15TO18</idno>
            <idno type="stamp" n="ANR-OCEANS">ANR-OCEANS</idno>
            <idno type="stamp" n="ANSES-PNREST">Anses – Programme national de recherche Environnement-Santé-Travail</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries</title>
                <author role="crp">
                  <persName>
                    <forename type="first">Manon</forename>
                    <surname>Lesage</surname>
                  </persName>
                  <email type="md5">642c637c80b50104b97802ff83128b38</email>
                  <email type="domain">inrae.fr</email>
                  <idno type="idhal" notation="string">manon-lesage</idno>
                  <idno type="idhal" notation="numeric">743015</idno>
                  <idno type="halauthorid" notation="string">50105-743015</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3121-5181</idno>
                  <affiliation ref="#struct-1002344"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Manon</forename>
                    <surname>Thomas</surname>
                  </persName>
                  <email type="md5">5b7f62a7ddde6ae82b17c36820ce44d7</email>
                  <email type="domain">inrae.fr</email>
                  <idno type="idhal" notation="string">manon-thomas</idno>
                  <idno type="idhal" notation="numeric">741968</idno>
                  <idno type="halauthorid" notation="string">50106-741968</idno>
                  <affiliation ref="#struct-1002344"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Thierry</forename>
                    <surname>Pécot</surname>
                  </persName>
                  <email type="md5">41a8830d6d3734601b1826344aa875f6</email>
                  <email type="domain">univ-rennes1.fr</email>
                  <idno type="idhal" notation="numeric">1128783</idno>
                  <idno type="halauthorid" notation="string">786684-1128783</idno>
                  <affiliation ref="#struct-453207"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Tu-Ky</forename>
                    <surname>Ly</surname>
                  </persName>
                  <email type="md5">52a99a4fbd3be451b51a1a7f203d1b61</email>
                  <email type="domain">gmail.com</email>
                  <idno type="idhal" notation="string">tuky-ly</idno>
                  <idno type="idhal" notation="numeric">1502622</idno>
                  <idno type="halauthorid" notation="string">2755960-1502622</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-4112-5312</idno>
                  <affiliation ref="#struct-3186"/>
                  <affiliation ref="#struct-254401"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nathalie</forename>
                    <surname>Hinfray</surname>
                  </persName>
                  <email type="md5">5de05b0ad6f226590a88f7a4b1d4d0e2</email>
                  <email type="domain">ineris.fr</email>
                  <idno type="idhal" notation="string">nathalie-hinfray</idno>
                  <idno type="idhal" notation="numeric">1011043</idno>
                  <idno type="halauthorid" notation="string">201055-1011043</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/Q-6625-2018</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-3887-6043</idno>
                  <affiliation ref="#struct-3186"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Rémy</forename>
                    <surname>Beaudouin</surname>
                  </persName>
                  <email type="md5">c3d7e34f16198007c25ccdcd34ad22a7</email>
                  <email type="domain">ineris.fr</email>
                  <idno type="idhal" notation="string">remybeaudouin</idno>
                  <idno type="idhal" notation="numeric">754091</idno>
                  <idno type="halauthorid" notation="string">38407-754091</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/H-1491-2012</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-2855-1571</idno>
                  <idno type="IDREF">https://www.idref.fr/12234071X</idno>
                  <affiliation ref="#struct-3186"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michelle</forename>
                    <surname>Neumann</surname>
                  </persName>
                  <idno type="halauthorid">2781008-0</idno>
                  <affiliation ref="#struct-442033"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Robin</forename>
                    <surname>Lovell-Badge</surname>
                  </persName>
                  <email type="md5">0497d8cd440e12e4e04aee44a640b1a8</email>
                  <email type="domain">crick.ac.uk</email>
                  <idno type="idhal" notation="numeric">1153855</idno>
                  <idno type="halauthorid" notation="string">546886-1153855</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9364-4179</idno>
                  <affiliation ref="#struct-442033"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jérôme</forename>
                    <surname>Bugeon</surname>
                  </persName>
                  <email type="md5">564a68025046287b3005cc370b11acc8</email>
                  <email type="domain">inrae.fr</email>
                  <idno type="idhal" notation="string">jerome-bugeon</idno>
                  <idno type="idhal" notation="numeric">739227</idno>
                  <idno type="halauthorid" notation="string">48032-739227</idno>
                  <idno type="IDREF">https://www.idref.fr/059683171</idno>
                  <idno type="ORCID">https://orcid.org/0009-0005-2042-3953</idno>
                  <affiliation ref="#struct-1002344"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">Violette</forename>
                    <surname>Thermes</surname>
                  </persName>
                  <email type="md5">94326621fb84b2e3d546db2bf28ec3a3</email>
                  <email type="domain">inrae.fr</email>
                  <idno type="idhal" notation="string">violette-thermes</idno>
                  <idno type="idhal" notation="numeric">738713</idno>
                  <idno type="halauthorid" notation="string">48036-738713</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0838-4155</idno>
                  <idno type="IDREF">https://www.idref.fr/088810062</idno>
                  <affiliation ref="#struct-1002344"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">4385</idno>
                <idno type="issn">0950-1991</idno>
                <idno type="eissn">1477-9129</idno>
                <title level="j">Development (Cambridge, England)</title>
                <imprint>
                  <publisher>Company of Biologists</publisher>
                  <biblScope unit="volume">150</biblScope>
                  <biblScope unit="issue">7</biblScope>
                  <biblScope unit="pp">dev201185</biblScope>
                  <date type="datePub">2023-03-27</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1242/dev.201185</idno>
              <idno type="pubmed">36971372</idno>
              <idno type="wos">001006289300001</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">3D imaging</term>
                <term xml:lang="en">Ovary</term>
                <term xml:lang="en">Fish</term>
                <term xml:lang="en">Deep learning segmentation</term>
                <term xml:lang="en">Clearing</term>
                <term xml:lang="en">Cellpose</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="vocinrae" n="c_25032">fish</classCode>
              <classCode scheme="vocinrae" n="c_25032">Pisces</classCode>
              <classCode scheme="vocinrae" n="c_8042">ovary</classCode>
              <classCode scheme="vocinrae" n="c_17460">3D imaging</classCode>
              <classCode scheme="vocinrae" n="c_14540">AI</classCode>
              <classCode scheme="vocinrae" n="c_14540">artificial intelligence</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Computational analysis of bio-images by deep learning (DL) algorithms has made exceptional progress in recent years and has become much more accessible to non-specialists with the development of ready-to-use tools. Study of oogenesis mechanisms and female reproductive success has also recently benefited from the development of efficient protocols for three-dimensional (3D) imaging of ovaries. Such datasets have a great potential for generating new quantitative data but are, however, complex to analyze due to the lack of efficient workflows for 3D image analysis. Here, we integrated two existing open-source DL tools, Noise2Void and Cellpose, into an analysis pipeline dedicated to 3D follicular content analysis and available on Fiji. Our pipeline was developed on larvae and adult medaka ovaries but was also successfully applied to different types of ovaries (trout, zebrafish and mouse). Image enhancement, Cellpose segmentation and label post-processing enabled automatic and accurate quantification of these 3D images exhibiting irregular fluorescent staining, low autofluorescence signal or heterogeneous follicles sizes. In the future, this pipeline will be useful for extensive cellular phenotyping in fish or mammals for developmental or toxicology studies.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1002344" status="VALID">
          <idno type="RNSR">199717864K</idno>
          <idno type="ROR">https://ror.org/04xtaw673</idno>
          <orgName>Laboratoire de Physiologie et Génomique des Poissons = Fish Physiology and Genomics Institute</orgName>
          <orgName type="acronym">LPGP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Campus de Beaulieu - Bât. 16A - 35042 RENNES Cedex [France]</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www6.rennes.inrae.fr/lpgp/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-453207" type="direct"/>
            <relation name="UR1037" active="#struct-577435" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-453207" status="VALID">
          <idno type="IdRef">200295462</idno>
          <idno type="RNSR">201220717W</idno>
          <idno type="ROR">https://ror.org/05cx7ek10</idno>
          <orgName>Structure Fédérative de Recherche en Biologie et Santé de Rennes</orgName>
          <orgName type="acronym">Biosit : Biologie - Santé - Innovation Technologique</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Rennes - Campus Santé Villejean -  2, avenue Professeur Léon Bernard 35043 Rennes cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://biosit.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-3186" status="VALID">
          <idno type="ROR">https://ror.org/034yrjf77</idno>
          <orgName>Institut National de l'Environnement Industriel et des Risques</orgName>
          <orgName type="acronym">INERIS</orgName>
          <desc>
            <address>
              <addrLine>Verneuil-en-Halatte ; Nancy ; Aix en Provence</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ineris.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-254401" status="VALID">
          <idno type="IdRef">196981344</idno>
          <idno type="RNSR">201420894E</idno>
          <idno type="ROR">https://ror.org/046cwyy43</idno>
          <orgName>Stress Environnementaux et BIOsurveillance des milieux aquatiques</orgName>
          <orgName type="acronym">SEBIO</orgName>
          <date type="start">2014-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Reims Champagne-ArdenneUMR-I 02 INERIS-URCA-ULH SEBIOUnité Stress Environnementaux et BIOsurveillance des milieux aquatiquesUFR Sciences Exactes et Naturelles, Campus du Moulin de la Housse, BP 103951687 Reims cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-reims.fr/minisite_55/</ref>
          </desc>
          <listRelation>
            <relation name="UMR-I 02" active="#struct-3186" type="direct"/>
            <relation name="UMR-I 02" active="#struct-7569" type="direct"/>
            <relation name="UMR-I 02" active="#struct-300317" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
            <relation active="#struct-522879" type="direct"/>
            <relation name="CNRS 3417" active="#struct-7569" type="direct"/>
            <relation name="CNRS 3417" active="#struct-441569" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-442033" status="VALID">
          <idno type="ROR">https://ror.org/04tnbqb63</idno>
          <orgName>The Francis Crick Institute [London]</orgName>
          <desc>
            <address>
              <addrLine>Mill Hill Laboratory, London</addrLine>
              <country key="GB"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-577435" status="VALID">
          <idno type="ROR">https://ror.org/003vg9w96</idno>
          <orgName>Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement</orgName>
          <orgName type="acronym">INRAE</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-7569" status="VALID">
          <idno type="IdRef">026403838</idno>
          <idno type="ISNI">0000000121767954</idno>
          <idno type="ROR">https://ror.org/03hypw319</idno>
          <orgName>Université de Reims Champagne-Ardenne</orgName>
          <orgName type="acronym">URCA</orgName>
          <desc>
            <address>
              <addrLine>2 avenue Robert Schuman, 51100 Reims.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-reims.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300317" status="VALID">
          <idno type="IdRef">031308570</idno>
          <idno type="ISNI">0000000121731046</idno>
          <idno type="ROR">https://ror.org/05v509s40</idno>
          <orgName>Université Le Havre Normandie</orgName>
          <orgName type="acronym">ULH</orgName>
          <date type="start">1984-08-27</date>
          <desc>
            <address>
              <addrLine>25 rue Philippe Lebon - BP 1123 - 76063 Le Havre Cedex France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-lehavre.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-455934" status="VALID">
          <idno type="IdRef">190906332</idno>
          <idno type="ISNI">0000000417859671 </idno>
          <idno type="ROR">https://ror.org/01k40cz91</idno>
          <orgName>Normandie Université</orgName>
          <orgName type="acronym">NU</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.normandie-univ.fr/</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-522879" status="VALID">
          <orgName>SFR Condorcet</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://sfr-condorcet.fr</ref>
          </desc>
          <listRelation>
            <relation name="CNRS 3417" active="#struct-7569" type="direct"/>
            <relation name="CNRS 3417" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-48334" status="VALID">
          <idno type="anr">ANR-18-CE20-0004</idno>
          <idno type="program">APPEL À PROJETS GÉNÉRIQUE 2018</idno>
          <orgName>DynaMO</orgName>
          <desc>Elucider les bases cellulaires de la fécondité chez le poisson : dynamique et régulation de l'ovogenèse chez le medaka</desc>
          <date type="start">2018</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>