Taking into account beliefs and culture is essential in behaviour analysis in various areas of life and work. However, knowledge about the links between these beliefs is sparse and imprecise. This article analyses the links between fatalistic, cultural and socio-instrumental control beliefs, by a questionnaire on a sample of 515 Cameroonian partcipants including male ( N = 290) and female ( N = 225), workers from the public ( N = 208), formal private ( N = 265) and informal ( N = 40) sectors. The questionnaire consisted of the fatalism scale designed by Kouabenan (1998), the Cameroonian cultural beliefs scale by Ngueutsa et al. (2021), and the socio-instrumental control beliefs scale derived from Spector (2004). Regression analyses showed that cultural beliefs partially mediated the link between fatalistic and socio-instrumental control beliefs. The results call into question the conceptualization of fatalistic beliefs, often seen as inducers of passivity. They suggest that cultural beliefs and practices may activate a ‘non-inhibiting’ form of fatalism that would justify the use of cultural entities to exercise indirect control over events. The concept of active fatalism is discussed.