α-Carbamoylsulfides as N -Carbamoylimine Precursors in the Visible Light Photoredox-Catalyzed Synthesis of α,α-Disubstituted Amines - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Organic Letters Année : 2016

α-Carbamoylsulfides as N -Carbamoylimine Precursors in the Visible Light Photoredox-Catalyzed Synthesis of α,α-Disubstituted Amines

Résumé

A general and practical photoredox-promoted addition of nucleophiles to N-acylimines generated in situ from α-amidosulfides using Ru(bpy)3(PF6)2 as the photocatalyst is reported. The broad scope of the reaction toward various nucleophiles and amidosulfide derivatives was explored. This novel protocol provides a rapid, mild, and efficient access to valuable α,α-disubstituted amines in respectable yields
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hal-04046905 , version 1 (27-03-2023)

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Clément Lebée, Morgan Languet, Clémence Allain, Géraldine Masson. α-Carbamoylsulfides as N -Carbamoylimine Precursors in the Visible Light Photoredox-Catalyzed Synthesis of α,α-Disubstituted Amines. Organic Letters, 2016, 18 (6), pp.1478-1481. ⟨10.1021/acs.orglett.6b00442⟩. ⟨hal-04046905⟩
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