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Article Dans Une Revue Sensors Année : 2023

A New Generation of OPM for High Dynamic and Large Bandwidth MEG: The 4He OPMs—First Applications in Healthy Volunteers

Rudy Romain
Sergey Mitryukovskiy
  • Fonction : Auteur
William Fourcault
  • Fonction : Auteur
Vincent Josselin
  • Fonction : Auteur
Matthieu Le Prado
  • Fonction : Auteur
Agustin Palacios-Laloy
Etienne Labyt

Résumé

MagnetoEncephaloGraphy (MEG) provides a measure of electrical activity in the brain at a millisecond time scale. From these signals, one can non-invasively derive the dynamics of brain activity. Conventional MEG systems (SQUID-MEG) use very low temperatures to achieve the necessary sensitivity. This leads to severe experimental and economical limitations. A new generation of MEG sensors is emerging: the optically pumped magnetometers (OPM). In OPM, an atomic gas enclosed in a glass cell is traversed by a laser beam whose modulation depends on the local magnetic field. MAG4Health is developing OPMs using Helium gas (4He-OPM). They operate at room temperature with a large dynamic range and a large frequency bandwidth and output natively a 3D vectorial measure of the magnetic field. In this study, five 4He-OPMs were compared to a classical SQUID-MEG system in a group of 18 volunteers to evaluate their experimental performances. Considering that the 4He-OPMs operate at real room temperature and can be placed directly on the head, our assumption was that 4He-OPMs would provide a reliable recording of physiological magnetic brain activity. Indeed, the results showed that the 4He-OPMs showed very similar results to the classical SQUID-MEG system by taking advantage of a shorter distance to the brain, despite having a lower sensitivity.

Dates et versions

hal-04038892 , version 1 (21-03-2023)

Licence

Domaine public

Identifiants

Citer

Tjerk Gutteling, Mathilde Bonnefond, Tommy Clausner, Sébastien Daligault, Rudy Romain, et al.. A New Generation of OPM for High Dynamic and Large Bandwidth MEG: The 4He OPMs—First Applications in Healthy Volunteers. Sensors, 2023, 23 (5), pp.2801. ⟨10.3390/s23052801⟩. ⟨hal-04038892⟩
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