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Article Dans Une Revue Chemical Physics Letters Année : 2023

First example of photorelease of nitric oxide from ruthenium nitrosyl-based nanoparticles

Résumé

We described the facile preparation of nanoparticles of a photoactivable ruthenium nitrosyl complex. Nanparticle sizes were investigated by atomic force microscopy and nanoparticle tracking analysis. For nanoparticles dispersed in water, nitric oxide (NO) photorelease was evidenced at 365 nm. The quantum yield of photorelease was found to be of about 0.04. Electron paramagnetic resonance as well as measurements by a NO sensor confirmed NO release upon photolysis of nanoparticles. This work showed that these nanoparticles allowed a spatiotemporal control of NO release upon light irradiation and are potential NO nanoplatforms for biological applications.
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Dates et versions

hal-04034750 , version 1 (17-03-2023)

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Paternité - Pas d'utilisation commerciale - Pas de modification

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Arij Farhat, Marine Tassé, Mathilde Bocé, D de Caro, Isabelle Malfant, et al.. First example of photorelease of nitric oxide from ruthenium nitrosyl-based nanoparticles. Chemical Physics Letters, 2023, 818, pp.140434. ⟨10.1016/j.cplett.2023.140434⟩. ⟨hal-04034750⟩
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