Battery lifetime is an important parameter in the life cycle assessment (LCA) of a plug-in hybrid-electric vehicle (PHEV). This paper aims to study the impact of various parameters on the battery aging of a PHEV. For this purpose, model-based use cases are generated, the outputs of which are the daily driven distances for a period of one year, recharge scenarios, and battery temperature. A combined aging model (calendar and cycling aging) is used to calculate the capacity lost by the battery at the end of one year of use. The thermal model of the battery is using an electro-thermal coupling equation, for which the ambient temperature is modeled using daily minimum and maximum temperature data varying throughout the year for different cities. Finally, a sensitivity analysis is carried out using the conditioned variance method to identify the most important input parameters which largely affect the output of this study. The results of this study show that battery size, annual mileage, external temperature, and charging behavior are the most important parameters to be considered in the aging study of the battery of a PHEV personal car.