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Communication Dans Un Congrès Année : 2023

Design of antibacterial molecules by photopharmacology (ECOPHOTOSKIN)

Muriel Billamboz
  • Fonction : Auteur
  • PersonId : 1103345
Muriel Vayssade

Résumé

Antibiotics are rejected in the environment after their use for treating human and animal bacterial infections. These residues are poorly eliminated by the actual wastewater treatment processes, impacting both animal, human and environmental health. This led to the emergence of antibiotic resistance in bacterial pathogens. To fight this issue, the last decades have been marked by the apparition of photopharmacology. This approach based on the use of the light is a promising way to control the antibiotic activity of a drug. Indeed, under a UV light irradiation, the drug is activated and exercises its antibacterial activity. In contrary, when the drug is released in the environment, its visible light illumination enables its deactivation. Thus, this work proposes the design of antibacterial molecules to be used for photopharmacology to treat bacterial infections.
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Dates et versions

hal-04011879 , version 1 (02-03-2023)

Identifiants

Citer

Amélie Aubert, Muriel Billamboz, Antoine Fayeulle, Muriel Vayssade, Estelle Léonard. Design of antibacterial molecules by photopharmacology (ECOPHOTOSKIN). Colloque InterUT Systèmes sûrs et durables, Université de Technologie de Compiègne [UTC], Feb 2023, Paris, France. ⟨10.34746/hm6j-hz82⟩. ⟨hal-04011879⟩
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