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Journal Articles Current Opinion in Genetics and Development Year : 1995

TFIIH: a link between transcription, DNA repair and cell cycle regulation

Abstract

TFIIH is a basal transcription factor for protein-coding genes. It contains ERCC2, ERCC3, MO15 and cyclin H, polypeptides implicated in nucleotide excision repair or cell cycle regulation. The dysfunction of TFIIH could result in a large panel of genetic disorders, such as xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy. This link between transcription, DNA repair and cell cycle has highlighted a complex and essential role for TFIIH in the cell and has provided much information on the molecular mechanisms of each of these cellular processes.
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hal-03995299 , version 1 (17-02-2023)

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Thierry Seroz, Jae Ryoung Hwang, Vincent Moncollin, Jean-Marc Egly. TFIIH: a link between transcription, DNA repair and cell cycle regulation. Current Opinion in Genetics and Development, 1995, 5 (2), pp.217-221. ⟨10.1016/0959-437x(95)80011-5⟩. ⟨hal-03995299⟩
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