Interplay of RNA 2′-O-methylations with viral replication
Abstract
Highlights • Viral RNA genomes are modified by epitranscriptomic marks, such as 2′-Omethylation. • 2′-O-methylations are self-markers hijacked by viruses to avoid immune sensing. • Modified viral RNA counteract restriction by interferon-stimulated genes. • New insights suggest that 2′-O-methylations also impair viral replication.
Domains
Life Sciences [q-bio]| Origin | Files produced by the author(s) |
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