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Journal Articles Current Opinion in Virology Year : 2023

Interplay of RNA 2′-O-methylations with viral replication

Abstract

Highlights • Viral RNA genomes are modified by epitranscriptomic marks, such as 2′-Omethylation. • 2′-O-methylations are self-markers hijacked by viruses to avoid immune sensing. • Modified viral RNA counteract restriction by interferon-stimulated genes. • New insights suggest that 2′-O-methylations also impair viral replication.
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Dates and versions

hal-03981798 , version 1 (10-02-2023)

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Alice Decombe, Priscila El Kazzi, Etienne Decroly. Interplay of RNA 2′-O-methylations with viral replication. Current Opinion in Virology, 2023, 59 (avril), pp.101302. ⟨10.1016/j.coviro.2023.101302⟩. ⟨hal-03981798⟩
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