To measure fuel rod swelling in a nuclear research reactor, our research has focused on the development of an optical confocal chromatic sensor, allowing contactless measurements of radial changes in fuel rods. This sensor must be able to operate in the harsh and hot environment of a reactor, especially under high neutron fluences up to 1019 nfast/cm2 and gamma doses of a few GGy. When exposed to such radiation levels, the properties of bulk optical glasses are known to be affected by two main phenomena: radiation-induced attenuation (RIA) and radiation-induced refractive index change (RIRIC). With the objective of testing glasses as candidates for a future confocal chromatic sensor, we created a dedicated setup for the online monitoring of the glasses’ RIRIC in the core reactor with a measurement principle relying on interferometry. Since not only the refractive index (RI) but also the length of the samples changes under neutron radiation through compaction, we measured the variation of the optical path (OP) ( nL ). To assess the performance of our setup, preliminary in-lab tests were performed to evaluate the feasibility of measuring the small RI changes caused by external temperature changes. Due to this study, we were able to obtain data that were not yet available in the literature regarding the temperature-induced RI variation of several bulk glasses, including radiation-hardened glasses, up to 350 °C. This information is crucial for the targeted application, as the confocal chromatic sensor will have to operate at such elevated temperatures.