Abstract The high vertical density soundings recorded during the 2006 African Monsoon Multidisciplinary Analysis (AMMA) campaign are assimilated into the French numerical weather prediction Action de Recherche Petite Echelle Grande Echelle (ARPEGE) four-dimensional variational data assimilation (4DVAR) system, with and without a bias correction for relative humidity. Four different experiments are carried out to assess the impacts of the added observations. The analyses and forecasts from these different scenarios are evaluated over western Africa. For the full experiment using all data together with a bias correction, the humidity analysis is in better agreement with surface observations and independent GPS observations than it was for the other experiments. AMMA data also improve the African easterly jet (AEJ) on its southeasterly side, and when they are used with an appropriate bias correction, the daily and monthly averaged precipitation results are in relatively good agreement with the satellite-based precipitation estimates. Forecast scores are computed with respect to surface observations, radiosondes, and analyses from the European Centre for Medium-Range Weather Forecasts (ECMWF). The positive impacts of additional radiosonde observations (with a relevant bias correction) are found to propagate downstream with a positive impact over Europe at the 2–3-day forecast range.