Synthesis and Anti-HSV-1 Activity of New 3-Amino-3-Arylpropionic Acid Esters
Résumé
A number of 3-methylbut-2-enyl esters of various 3-amino-3-arylpropionic acids have been synthesized and tested for antiviral activity against HSV-1. Many of these compounds, analogues of the 3-methylbut-2-enyl caffeate, isolated from poplar buds, show marked anti-HSV-1 activity and are less toxic than the natural ester.