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Article Dans Une Revue Synthesis: Journal of Synthetic Organic Chemistry Année : 2021

Aminothiaindanone as an Accessible Scaffold for a Three-Point Chemical Diversity

Pauline Zipfel
  • Fonction : Auteur
Julien Lalut
  • Fonction : Auteur
Patrick Dallemagne

Résumé

Abstract Aminothiaindanone heterocycle appears to be a scaffold of interest in medicinal chemistry. To increase the chemical diversity in this series, the introduction of three-point chemical diversity on the cyclopenta[b]thiophen-4-one scaffold was explored. About thirty newly functionalized thiophene-containing bicycles were obtained using various chemical reactions, paving the way for novel possibilities in medicinal chemistry projects.

Domaines

Chimie
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Dates et versions

hal-03969969 , version 1 (02-02-2023)

Identifiants

Citer

Pauline Zipfel, Julien Lalut, Jana Sopková-de Oliveira Santos, Christophe Rochais, Patrick Dallemagne. Aminothiaindanone as an Accessible Scaffold for a Three-Point Chemical Diversity. Synthesis: Journal of Synthetic Organic Chemistry, 2021, 53 (20), pp.3799-3814. ⟨10.1055/a-1523-1409⟩. ⟨hal-03969969⟩
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