Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins - Archive ouverte HAL Access content directly
Journal Articles Nature Communications Year : 2023

Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins

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Lars B Scharff

Abstract

The current agriculture main challenge is to maintain food production while facing multiple threats such as increasing world population, temperature increase, lack of agrochemicals due to health issues and uprising of weeds resistant to herbicides. Developing novel, alternative, and safe methods is hence of paramount importance. Here, we show that complementary peptides (cPEPs) from any gene can be designed to target specifically plant coding genes. External application of synthetic peptides increases the abundance of the targeted protein, leading to related phenotypes. Moreover, we provide evidence that cPEPs can be powerful tools in agronomy to improve plant traits, such as growth, resistance to pathogen or heat stress, without the needs of genetic approaches. Finally, by combining their activity they can also be used to reduce weed growth.
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Dates and versions

hal-03949768 , version 1 (20-01-2023)

Licence

Attribution - CC BY 4.0

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Mélanie Ormancey, Bruno Guillotin, Rémy Merret, Laurent Camborde, Carine Duboé, et al.. Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins. Nature Communications, 2023, 14 (1), pp.254. ⟨10.1038/s41467-023-35951-0⟩. ⟨hal-03949768⟩
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