The Role of Lebanon in the COVID-19 Butterfly Effect: The B.1.398 Example - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Viruses Année : 2022

The Role of Lebanon in the COVID-19 Butterfly Effect: The B.1.398 Example

Marwan Osman

Résumé

In the present study, we provide a retrospective genomic surveillance of the SARS-CoV-2 pandemic in Lebanon; we newly sequence the viral genomes of 200 nasopharyngeal samples collected between July 2020 and February 2021 from patients in different regions of Lebanon and from travelers crossing the Lebanese–Syrian border, and we also analyze the Lebanese genomic dataset available at GISAID. Our results show that SARS-CoV-2 infections in Lebanon during this period were shaped by the turnovers of four dominant SARS-CoV-2 lineages, with B.1.398 being the first to thoroughly dominate. Lebanon acted as a dispersal center of B.1.398 to other countries, with intercontinental transmissions being more common than within-continent. Within the country, the district of Tripoli, which was the source of 43% of the total B.1.398 sequences in our study, was identified as being an important source of dispersal in the country. In conclusion, our findings exemplify the butterfly effect, by which a lineage that emerges in a small area can be spread around the world, and highlight the potential role of developing countries in the emergence of new variants.
Fichier principal
Vignette du fichier
viruses-14-01640.pdf (2.11 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03941987 , version 1 (16-01-2023)

Licence

Paternité

Identifiants

Citer

Dalal Nour, Rayane Rafei, Alessandra P Lamarca, Luiz G P de Almeida, Marwan Osman, et al.. The Role of Lebanon in the COVID-19 Butterfly Effect: The B.1.398 Example. Viruses, 2022, 14 (8), pp.1640. ⟨10.3390/v14081640⟩. ⟨hal-03941987⟩
45 Consultations
32 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More