Imagerie et analyse des parois d’artères par micro-tomographie aux rayons X synchrotron
Résumé
Vascular ageing is characterized by profound modifications of the large elastic arteries (mainly aorta), leading to consequences such as aneurysm formation. Age-related diseases can be precipitated by metabolic disorders, e.g. diabetes or chronic kidney diseases. Vascular diseases involve morphological changes of the arterial extracellular matrix, particularly remodelling of the elastic lamellae found in the wall. Synchrotron X-ray microtomography (μCT ) gives access to images with a micrometric resolution.
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